Molecular Formula:C22H30Br2Cl2N2 Compound Is Canonicalized:True XLogP3-AA:552.01323 Monoisotopic Mass:550.01528 Complexity:348 Rotatable Bond Count:8 Hydrogen Bond Donor Count:4 Hydrogen Bond Acceptor Count:2 Topological Polar Surface Area:24.1 Heavy Atom Count::28 Defined Atom Stereocenter Count:0 Un...
The complexes are soluble in polar solvents, including water. The terpyridine moiety binds the metal in a κ-N,N,N mode. Analytical data are consistent with the proposed structures in Scheme 1. Elemental analysis reveals an empirical formula of M(PTA–Bztpy)2Br2 (M = Co, Ni, Mn), ...
For the stepwise protocol outlined below, Tet-controlled (Tet-On) expression of a paradigm MSI driver gene (TGFBR2) in a typical MMR- and TGFBR2-deficient colorectal cancer cell line (HCT116) has been chosen as an example. In the first genetic modification step (Fig. 2A), t...