Alzheimer disease ‐ current and future therapiesAPP AND Aβ‐specific therapeutic targets ‐ Aβ production by β‐ and g‐secretase cleavage of APP, one of the most pivotal points for therapeutic intervention in ADTAU‐specific therapeutic targets ‐ hyperphosphorylated TAU as paired helical ...
Stem cell therapy for Alzheimer's disease and related disorders: current status and future perspectives Underlying cognitive declines in Alzheimer's disease (AD) are the result of neuron and neuronal process losses due to a wide range of factors. To date, all efforts to develop therapies that ta...
combined with testing for disease-susceptibility genes, could be the most effective approach to reduce the incidence. This article aims to review the current status of disease-modifying therapies and prevention of Alzheimer’s disease. Keywords:Dementia, review, Alzheimer’s Disease, Disease-Modifying ...
Scheme depicting cellular and molecular processes that happen at the level of the brain parenchyma, meningeal dura, and central nervous system (CNS)-draining cervical lymph nodes in the young and healthy state (illustrations to the left), or during aging and in Alzheimer’s disease (illustrations ...
Moreover, MSCs are easily expandable in vitro and hence MSCs are used in many clinical trials targeting a huge range of diseases and conditions from neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, autoimmune disease such as multiple sclerosis to injury conditions such...
Alzheimer’s disease ALS: Amyotrophic lateral sclerosis ASCs: Adipose stem/progenitor cells bFGF: Basic fibroblast growth factor BMMSCs: Bone-marrow-derived mesenchymal stem/progenitor cells BMP: Bone morphogenetic protein BNDF: Brain-derived neurotrophic factor BSP: Bone sialoprotein CCK-8:...
Citation104 The findings emphasize the potential of utilizing PELNs for COVID-19 treatment, particularly in light of the urgent need for effective therapies during the rapid spread of the disease, warranting further investigation. Furthermore, PELNs also hold promise for the treatment of pulmonary ...
(2013). Current and emerging therapies for Alzhei- mer's disease. Clin. Ther. 35, 1480-1489.H.B. Nygaard, Current and emerging therapies for Alzheimer's disease, Clin. Ther. 35 (10) (2013) 1480-1489.Nygaard HB. Current and emerging therapies for Alzheimer's disease. Clinical ...
Alzheimer disease current and future therapiesAPP AND Aβ﹕pecific therapeutic targets Aβ production by βand g﹕ecretase cleavage of APP, one of the most pivotal points for therapeutic intervention in ADTAU﹕pecific therapeutic targets hyperphosphorylated TAU as paired helical filaments (PHFs)...
doi:10.13183/JECNS.V2I1.19Mohammad Reza Bolouri