Since its discovery in sheep reticulocytes in the 1880s, exosomes have been widely investigated for their potential applications in the diagnosis and treatment of various diseases. Although MDEs currently dominate the field of disease diagnosis, such as the detection of glioblastoma cell-derived EVs ...
Rathore S, Habes M, Iftikhar MA, Shacklett A, Davatzikos C (2017) A review on neuroimaging-based classification studies and associated feature extraction methods for Alzheimer's disease and its prodromal stages. NeuroImage 155:530–548. https://doi.org/10.1016/j.neuroimage.2017.03.057 Article ...
Proteotoxicity and cardiac dysfunction—Alzheimer’s disease of the heart? N Engl J Med. 2013;368:455–64. doi:10.1056/NEJMra1106180. CAS PubMed Google Scholar Haykowsky MJ, Brubaker PH, Morgan TM, Kritchevsky S, Eggebeen J, Kitzman DW. Impaired aerobic capacity and physical functional ...
Effect of flavonoids rich extract of Capparis spinosa on inflammatory involved genes in amyloid-beta peptide injected rat model of Alzheimer’s disease. Nutr. Neurosc. 2016, 1, 143–150. [Google Scholar] Wojdyło, A.; Nowicka, P.; Grimalt, M.; Legua, P.; Almansa, M.S.; Amoros, A....
Of the 23 most recently identified marine-derived compounds, 21 are in several different stages of the clinical pipeline for use as anticancer agents, while two of them are being assessed for treatment of chronic pain and neurological disorders like schizophrenia and Alzheimer’s disease [7]. In...
Carotenoids, also known as provitamin A, are lipophilic pigments that are classified into two groups, carotenes and xanthophylls, based on their polarity. The blood concentrations of carotenoids were found to be decreased in the elderly and in Alzheimer’s disease patients [125]. Huang et al. ...
We aimed to evaluate the impact of sequential anodal-tDCS on cognitive functions, functional segregation, and integration parameters in patients with MCI, according to high-risk factors for Alzheimer’s disease (AD): amyloid-beta (Aβ) deposition and APOEε4-allele status. In 32 patients with ...
Zhang B, Li Q, Chu X, Sun S, Chen S. Salidroside reduces tau hyperphosphorylation via up-regulating GSK-3β phosphorylation in a tau transgenic Drosophila model of Alzheimer’s disease. Transl Neurodegener. 2016;5:21. https://doi.org/10.1186/s40035-016-0068-y. Fitzenberger E, Deusing ...
Along similar lines, disease models for many other neurological disorders have been developed to date, including Rett syndrome [118], Down syndrome [119], Parkinson’s disease [120], and Alzheimer’s disease [121]. This iPSC technology has also been used to model various cardiac diseases ...
It must be remembered that these compounds have been held responsible for different degenerative diseases such as cancer, Alzheimer’s, or Parkinson’s among others [104,105,106]. Finally, it remains to be added that an important number of the above-mentioned compounds have been detected for ...