Roussel, M, Dull, T, Rettenmier, C, Ralph, P, Ullrich, A, Sherr, C (1987) Trans- forming potential of the c fins proto-oncogene (CSF-1 receptor). Nature 325: pp. 549-552Roussel MF, Dull TJ, Rettenmier CW, Ralph P, Ullrich A, Sherr CJ (1987) Transforming potential of the ...
The CSF-1 receptor (CSF-1R) is activated by the homodimeric growth factors colony-stimulating factor-1 (CSF-1) and interleukin-34 (IL-34). It plays important roles in development and in innate immunity by regulating the development of most tissue macrophages and osteoclasts, of Langerhans cell...
近日,中国科学院大学的研究人员报道了一款对FLT-3有选择性的CSF-1R抑制剂,其研究成果以Novel Class of Colony-Stimulating Factor 1 Receptor Kinase Inhibitors Based on an o‑Aminopyridyl Alkynyl Scaffffold as Potential Treatment for Infl...
A 5′ untransiated exon of the human CSF-1 receptor gene (c- fms) is separated by a 26 kb intron from the 32 kb receptor coding sequences. Nucleotide sequence analysis of cloned genomic DNA revealed that the 3′ end of the PDGF receptor gene is located less than 0.5 kb upstream from...
Tu2027 Treatment with the CSF-1 Receptor kinase (CSF-1R) Inhibitor JNJ40346527 Suppresses Murine ColitisA goal of the Airway Disease Endotyping for Personalized Treatment of Asthma (ADEPT) non-interventional study was to identify molecular pathways responsible for distinct asthma phenotypes. Four ...
英文名称:CD115 (Macrophage Colony-stimulating Factor 1 Receptor, CSF-1 Receptor, CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, CSF1R, FMS) 英文同义词:CD115 (Macrophage Colony-stimulating Factor 1 Receptor, CSF-1 Receptor, CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, CSF...
Colony stimulating factor-1 (CSF-1) and its receptor (CSF-1R) are key regulators of macrophage biology, and their elevated expression in cancer cells has been linked to poor prognosis. CSF-1Rs are thought to function at the plasma membrane. We show here that functional CSF-1Rs are present...
The integration of all of these parameters is required to fully understand the complex role of coregulators in nuclear receptor gene transcription. Glossary co-activator A biomolecule (predominantly protein) that interacts with transcription factors to enhance tran- scription factor-dependent target gene...
CSF -1/CSF -1R 抑制剂的应用在很大程度上延缓了肿瘤的发展，并协同促进免疫治疗的临床疗效。［关键词］CSF -1/CSF -1R ；肿瘤微环境；免疫治疗；TAM ；MDSCs ；DCs Progress of CSF -1and its receptor in tumor microenvironment and immuno -therapy SHEN Jing -Yi ，HAO Yan -Rong.Guangxi University ...
产品名称:Phycoerythrin (PE) anti-human CD115 (CSF-1R, FMS, CSF-1 Receptor) 100 tests .0订购此产品 供应商:Ebioscience 规格:100 tests 目录价:3708 库存状态: CAS编号: 应用范围: 种属来源: 相关信息: 保存条件: 说明书地址:点击查看详细