The meaning of CREATINE KINASE is any of three isoenzymes found especially in vertebrate skeletal and myocardial muscle that catalyze the transfer of a high-energy phosphate group from phosphocreatine to ADP with the formation of ATP and creatine.
Creatine kinase is a dimer that exists as isoenzymes with greatest activity in muscle (CK-MM), heart (CK-MB), and brain (CK-BB) (Lang, 1981). An additional form of the CK enzyme exists in mitochondria (CK-Mt). The distribution of CK isoenzymes varies between tissues and species. ...
Creatine kinase isoenzymesThe CK-BB levels in specific organs are listed in Table 1. The data given on total CK activity of human tissues represent a summary and compromise of the results obtained by various authors and with different methods. Similar data also have been published by Klein et...
the isoenzymes of creatine kinase. Creatine kinase is a dimer with M (muscle) and/or B (brain) subunits; it exists in three isoenzyme forms: CK-MM, the predominant form, found primarily in skeletal muscle; CK-MB, found in cardiac muscle, tongue, diaphragm, and in small amounts in skel...
Creatine kinase (CK) isoenzymes were determined on 15 patients undergoing open heart surgery with bypass. The study was performed to examine the relationship between the hypothermia under which the surgery is conducted and the appearance of CK isoenzymes in the serum both during and after surgery....
Creatine kinase activity was determined in 103 clinically healthy dogs. Normal values of total creatine kinase and its isoenzymes have been established, and our method of electrophoresis is described. The normal range of the total-CK activity in dog was higher than that in man (up to 84 U./...
Creatine Kinase is a dimeric enzyme composed of M and/or B subunits which associate to form the CK-MM, CK-MB and CK-BB isoenzymes.1,2Following myocardial infarction the CK-MM level rises and reaches a peak between 18-30 hrs, the increase being similar to that of the total CKactivity....
In muscle and nerve, most of the creatine is phosphorylated to phosphocreatine (pCr) in a reaction that is catalyzed by the enezyme creatine kinase (CK), there are three isoforms of (isoenzymes) of CK. CK-MM is the skeletal muscle isoform; CK-BB, the brain isoform, and CK-MB, the ...
临床化学分析方法:Creatine_Kinase_Isoenzymes Kaplan: Clinical Chemistry, 5th Edition Clinical References - Methods of Analysis Creatine Kinase Isoenzymes Mauro Panteghini i Name: Creatine kinase (CK, adenosine triphosphate: creatine N-phosphotransferase)Clinical significance:click here Enzyme number: EC ...
Fig. 1. The creatine kinase/phosphocreatine system. Compartment-specific isoenzymes of creatine kinase (CK) are found in mitochondria (sMtCK, uMtCK, left) and cytosol (MM-CK, BB-CK, MB-CK, right). They are either associated with ATP-delivering processes (oxidative phosphorylation or glycolysis...