Gastrointestinal symptoms in Parkinson's disease (PD) are among the most prevalent and debilitating of complications and present unique diagnostic and management challenges. Patients with PD commonly experience dysphagia, nausea, bloating, and constipation related to pathologic involvement of the enteric ...
neurodegenerative diseases, ischemia, nerve injury, pain, paresis, and neuropathy. These studies looked at the effects of laser therapy in combination with other therapies like pharmacotherapies, physical therapies, exercises, stem cells, and experimental materials on...
Over time, some individuals may develop tolerance to the effects of ASMs, leading to decreased seizure control. The brain’s adaptability and compensatory mechanisms may reduce the long-term efficacy of certain medications, necessitating the need for alternative therapeutic approaches [32]. Furthermore...
the presence of depressive symptoms was based on a cross-sectional design; the evaluation of benefits in functionality after the completion of CGC implicated a longitudinal design investigating the cohort of geriatric patients (those with depressive symptoms and those without) treated in the department....
In diabetes, Parkinson’s illness, and cancer, each JNK protein has different functions. Licochalcone A, a major phenolic component isolated from licorice root, inhibited JNK1 activity in vitro but had minimal influence on JNK2 activity. The simulation model demonstrated that licochalcone A inhibits...
The chemistry of these EOs has been extensively studied since the 1960s, but according to Dyer [8] only about 10% of Piper species species (112 of 1457 accepted species world-wide, www.theplantlist.org) has been phytochemically studied. For this review it was possible to find chemical ...
The “amyloid hypothesis” states that the accumulation of Aβ in the brain is responsible for the development of AD and the associated behavioral and cognitive symptoms [50]. This hypothesis has been at the forefront of AD research for the past decades. However, its potential as a therapeutic...