DiFeo TJ (2003) Drug product development: A technical review of chemistry, manufacturing, and controls information for the support of pharmaceutical compound ... DiFeo,J Thomas - 《Drug Development & Industrial Pharmacy》 被引量: 29发表: 2003年 Chemistry, Manufacturing and Control (CMC) Evaluations...
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Other formulations may conveniently be presented in unit dosage form, e.g., tablets and sustained release capsules, and in liposomes, and may be prepared by any methods well known in the art of pharmacy. Pharmaceutical formulations are usually prepared by mixing the active substance, or a ...
Polygonumins A, a new compound, was isolated from the stem ofPolygonum minus. Based on NMR results, the compound’s structure is identical to that of vanicoside A, comprising four phenylpropanoid ester units and a sucrose unit. The structure differences were located at C-3″″′. The cytoto...
Paller CJ and Antonarakis ES: Cabazitaxel: a novel second-line treatment for metastatic castration-resistant prostate cancer. Drug Des Dev and Ther 2011; 5: 117-24. Nightingale G and Ryu J. Cabazitaxel (jevtana): a novel agent for metastatic castration-resistant prostate c...
IMI is a drug whose therapeutic effect is achieved after several weeks of treatment. Considering the literature data confirming the antioxidant activity of both IMI and Zn, as well as the results of behavioral tests of the presented work, it seems reasonable to conduct future studies on the ...
Natural naphthoquinones and their derivatives exhibit a broad spectrum of pharmacological activities and have thus attracted much attention in modern drug discovery. However, it remains unclear whether naphthoquinones are potential drug candidates for anti-angiogenic agents. The aim of this study was to ...
Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia 7 Laboratory Department, Almadah General Hospital, Ministry of Health, Riyadh 10336, Saudi Arabia 8 Dipartimento di Medicina Molecolare e Traslazionale, Università Degli ...
Department of Pharmacy, Faculty of Pharmacy, Universitas Halu Oleo, Kendari 93232, Indonesia 2 Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Bandung 45363, Indonesia 3 Department of Analytical Pharmacy and Medicinal Chemistry, Faculty of Pharmacy, Universitas...
Being small molecules (MW range from 295.3–327.5), most of the physicochemical properties of these compounds fell into the drug-like chemical space, except the lipophilicity indices (logP and logD). This means that these compounds may have a drug-like behavior including appropriate pharmacokinetic...