Collagenase,TypeVIII可以水解TypeVIIIcollagen,可能用于研究动脉粥样硬化形成。TypeVIIIcollagen是内皮细胞分化和血管生成的调节剂,是平滑肌细胞等细胞粘附和迁移的底物,并可能在动脉粥样硬化中积累。内毒素激活Collagenase,TypeVIII表达后,可减少TypeVIIIcollagen产生,有潜力抑制动脉粥样硬化。REFERENCES[1].PlenzGA,etal....
Collagenase consists of different types, such as I, II, III, IV, V, VI VII, VIII, XI, and a special collagenase for liver cells. Collagenase from Clostridium histolyticum is classified into 6 groups, namely, viz, alpha, beta, gamma, delta, epsilon, and zeta. It serves as an important...
It also cleaves collagens type VII, VIII, and X, in addition to gelatine (nontriple helical collagen) and proteoglycan. It is an endopeptidase that catalyzes the hydrolytic cleavage of the triple helical portions of collagens I, II, and III at the one-quarter/three-quarter site. It is a...
CAS No. 9001-12-1 Chemical Name: Collagenase Synonyms FIBROBLAST;Collagenase IV;Collagenase clostridium histolyticum;Santyl;INTERSTITIAL;Collagenase A;Collagenase II;COLLAGENASE TYPE XI;COLLAGENASE TYPE VII HIGH PURITY;CLGN CBNumber: CB2112176 Molecular Formula: ...
C2139 release of rat epididymal adipocytes and hepatocytes tested (for methodology see Type II and Type IV), Type VIII, 0.5-5.0 FALGPA units/mg solid, ≥125 CDU/mg solid (CDU = collagen digestion units) (Sigma)C9263 release of physiologically active rat pancreatic islets tested, Type V, ...
Enzyme Collagenase Type VIII (), ELISA Kit (#MBS167670) Human Enzyme Collagenase Type VIII () ELISA Kit Host/Reactivities: Reactivity: Human MBS167670 48-Strip-Wells $260 96-Strip-Wells $395 5x96-Strip-Wells $1610 10x96-Strip-Wells $3135 Collagenase, Recombinant Protein (#MBS10...
Collagenase products are crucial to isolate primary cells in basic research and clinical therapies, where their stability in collagenolytic activity is required. However, currently standard collagenase products from Clostridium histolyticum lack such sta
Results of our biophysical studies suggest that this peculiar consensus sequence stabilizes a type VIII 尾-turn in several similar, but not identical, peptides that maintain a sufficient conformation to be recognized by the elastin receptor. We have also established that G XX PG elastin-derived ...
TFA from a solid support; v) adding resin attached with synthesized peptides to a flask and cooling the peptides; vi) washing the peptides with DCM and adding diethylether; vii) centrifuging the mixture to obtain sediments and eliminating supernatant; and viii) purifying the remaining sediments...