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1c). Furthermore, compared with human normal liver cells (L02), the MAPKAPK5-AS1 expression level was significantly upregulated in HCC cell lines (all p < 0.05, Additional File 3: Fig. S1B). Next, based on median MAPKAPK5-AS1expression in HCC tissues, patients were divided into ...
Statello L, Guo C-J, Chen L-L, Huarte M. Gene regulation by long non-coding RNAs and its biological functions. Nat Rev Mol Cell Biol. 2021;22(2):96–118. Article CAS PubMed Google Scholar Ni T, Huang X, Pan S, Lu Z. Inhibition of the long non-coding RNA ZFAS1 attenuates...
Drapkin B, Minna J. A rational targeted therapy for platinum-resistant small-cell lung cancer. Cancer Cell. 2021;39:453–6. Article CAS Google Scholar Dunne V, Ghita M, Small D, Coffey C, Weldon S, Taggart C, et al. Inhibition of ataxia telangiectasia related-3 (ATR) improves therap...
Scatter plot (A), Volcano plots (B) and heat map (C) showing expression profiles of long non-coding RNAs (lncRNAs) and mRNAs in inflammatory and normal long head of biceps tendon (LHBT). Three plots are based on the expression values of all lncRNAs and mRNAs detected by microarray. Thes...
aPKC-iota/P-Sp1/Snail signaling induces epithelial-mesenchymal transition and immunosuppression in cholangiocarcinoma. Hepatology. 2017;66:1165–82. Article CAS Google Scholar Kim WY, Jang JY, Jeon YK, Chung DH, Kim YG, Kim CW. Syntenin increases the invasiveness of small cell lung cancer ...
Our study verified that MK5 promoted the phosphorylation of c-Jun, which activated the transcription of SNAI1 by directly binding to its promoter. Conclusions : MK5-AS1 cis -regulated the nearby gene MK5 and acted as a let-7f-1-3p sponge, playing a vital role in CRC tumorigenesis. This...
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