The cause of deficiency of folate is often found in the past 6 months, whereas vitamin B12 deficiency due to autoimmune pernicious anemia or food-B12 malabsorption presents insidiously. Upon clinical suspicion of deficiency, conventional tests for serum folate and vitamin B12 are appropriate, and ...
Jean-Louis Schlienger, Jean-Frédéric Blicklé Abstract VITAMIN B12 OR COBALAMIN DEFICIENCY occurs frequently (> 20%) among elderly people, but it is often unrecognized because the clinical manifestations are subtle; they are also potentially serious, particularly from a neuropsychiatric and hematologica...
vitamin B12 n. a complex water-soluble solid, C63H88N14O14PCo, obtained from liver, milk, eggs, fish, oysters, and clams: a deficiency causes pernicious anemia and disorders of the nervous system. Also calledcyanocobalamin,cobalamin,extrinsic factor. ...
Background: Among micronutrients, vitamin B12 (B12) and folate (FA) are critical as they are required in a plethora of metabolic and biological functions. Hence, the present study was conducted for assessing the prevalence of cobalamins and folate deficiency amongst adolescen...
Vitamin B 12 DeficiencyVitamin E DeficiencyVitaminsChildAtaxiaThe catalytic properties of many enzymes depend on the participation of vitamins as obligatory cofactors. Vitamin B12 (cobalamin) and folic acid (folate) deficiencies in infants and children classically present with megaloblastic anemia and are ...
Vitamin B12 (cobalamin, Cbl) is required as a cofactor by two human enzymes, 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR) and methylmalonyl-CoA mutase (MMUT). Within the body, a vast array of transporters, enzymes and chaperones are required for the generation and delivery of the...
The functional relationship between vitamin B12 and folate explains why deficiency of any of them results in the same type of anemia. Cobalamin deficiency causes anemia due to a secondary lack of folate. In blood, pancytopenia, immature red blood cells, and hypersegmented granulocytes are observed....
What is vitamin B12? Also referred to as Cobalamin, it is an important vitamin that is necessary for a number of vital functions of the body. Along with the B vitamin folate, it helps create the genetic material of the human body. It helps maintain the levels of the amino acid known as...
The multi-faceted basis of vitamin B12 (cobalamin) neurotrophism in adult central nervous system: Lessons learned from its deficiency. Glial cells, myelin and the interstitium are the structures of the mammalian central nervous system (CNS) mainly affected by vitamin B (cobalamin, Cbl) def......
n.a B vitamin that is used to treat pernicious anemia 同义词:vitamin B12cyanocobalaminantipernicious anemia factor 学习怎么用 权威例句 Neurologic aspects of cobalamin deficiency. Vitamin B12 (cobalamin) deficiency in elderly patients. High Prevalence of Cobalamin Deficiency in Elderly Outpatients ...