The nuclear factor–erythroid-2–related factor 2 (Nrf2) is a master regulator of many antioxidants and can be activated under oxidative stress to initiate cell defense via upregulation of antioxidant enzymes, such as NAD(P)H dehydrogenase quinone 1 (NQO1), catalase, heme oxygenase 1 (HO1),...
Current Issues and New PerspectivesAdolescent Substance Use: Prevention and Intervention StrategiesAdolescent-to-Parent Violence: Psychological and Contextual InfluencesAdolescents’ Psychological Well-Being in Contemporary Contexts: The Role of the Parental Characteristics and RelationshipsAdvanced Treatment and Care...
There are many etiological questions that remain as to how COVID-19 intersects with CVD. The etiology of acute COVID-19 CVD adverse events like myocarditis [5], an inflammation of the heart valves often associated with viral infection, is more straightforward. However, the causes of chronic re...
Depression after exposure to stressful events: Lessons learned from the severe acute respiratory syndrome epidemic. Compr. Psychiatry 2012, 53, 15–23. [Google Scholar] [CrossRef] Julliard, K.; Klimenko, E.; Jacob, M.S. Definitions of health among healthcare providers. Nurs. Sci. Q. 2006...
DNA damage produced by ROS production activates PARP1, which leads to NAD+ depletion, decreasing SIRT1 activity. Theophylline inhibits PARP1, decreases ROS production, and enhances SIRT1 expression and activity. mTOR inhibition by theophylline contributes to attenuating the inflammatory response. The ...
To determine whether quaternary ammonium (k21) binds to Severe Acute Respiratory Syndrome–Coronavirus 2 (SARS-CoV-2) spike protein via computational molecular docking simulations, the crystal structure of the SARS-CoV-2 spike receptor-binding domain complexed with ACE-2 (PDB ID: 6LZG) was downlo...
Worldwide, healthcare systems had to respond to an exponential increase in COVID-19 patients with a noteworthy increment in intensive care units (ICU) admissions and invasive mechanical ventilation (IMV). The aim was to determine low intensity respiratory muscle training (RMT) effects in COVID-19...