Circulating tumor cells (CTCs) in breast cancer: a diagnostic tool for prognosis and molecular analysis生物学分析,肿瘤细胞,诊断工具,CTCS,高分子,乳腺癌,预后,循环变形乳癌(MBC ) 被肿瘤生长,增长和变形前进的联合描绘并且典型地与辩解的目的被管理。标准全身的治疗的利益是相对有限的,疾病被认为医不好建议...
mesenchymal transition (EMT) of tumor cells9, the role of exosomes in supporting metastasis10, circulating tumor cells (CTCs) and CTC clusters in seeding metastatic colonies11, and complex interactions between tumor cells and microenvironment12, have gradually been unmasked, along with the discovery o...
mesenchymal transition (EMT) of tumor cells9, the role of exosomes in supporting metastasis10, circulating tumor cells (CTCs) and CTC clusters in seeding metastatic colonies11, and complex interactions between tumor cells and microenvironment12, have gradually been unmasked, along with the discovery o...
Furthermore, the dynamics of CTC propagation are becoming recognized as an equally important component for the dissemination of tumor cells.111,126Chronotherapy has been used to study and evaluate the clinical application of the circadian rhythm’s function in tumor onset127,128and growth dynamics.129...
circulating tumor cell、HCC Abstract Purpose: Circulating tumor cells (CTCs) are considered potential biomarkers for the detection of hepatocellular carcinoma (HCC). Many studies have attempted to explore this role, but the results are variable. We conducted the first comprehensive meta-analysis to...
顾名思义,循环肿瘤细胞(CTCs)是肿瘤患者外周血中罕见的细胞。它们已被证明是许多癌症类型中有用的预后标记。在过去的十年里,人们发展了各种方法来检测癌症病人液体活检中的稀有细胞。这些方法揭示了CTCs的表型多样性,以及它们如何代表肿瘤中发现的补体细胞。单细胞蛋白质基因组学已经成为CTC研究的新一代技术方法。
cellsEarlycolorectalcancerPrognosisThe identification of patients at higher risk of recurrence after primary colorectal cancer resection is currently one of the challenges facing medical oncologists. Circulating tumor cell (CTC) may represent a surrogate marker of an early spread of disease in patients ...
Lyse cells with Trizol®. CTC ProcessingApproaches for the study of cancer cells: - RNA/DNA isolation - Cell culture experiments Results Fig. 1a and 1b: Flow cytometric analysis of Caco-2 cells, staining with anti-EpCAM-PE. Fig 2a: Colon carcinoma Caco-2 cells captured by EpCAM-pluri...
cells in five different classes with an accuracy, sensitivity and specificity of over 96%, and the obtained CTC counts predict the overall survival of cancer patients as well as state-of-the-art manual counts. Moreover, our network excelled in identifying different important subclasses of objects...
While numerous CTCs and CTC clusters are shed as the primary tumor grows, the dissemination process remains highly inefficient, with only a small fraction (approximately 0.02%) of these rare cells successfully completing the metastatic cascade and forming secondary tumors [1,2,3,4,5]. This fact...