Imipenem is the first of the carbapenems – a new class of β-lactam antibiotics. It is combined with cilastatin, a non-antibiotic enzyme inhibitor which prevents the breakdown of imipenem to nephrotoxic metabolites. The combination (Primaxin – MSD) is available only for intravenous use. ...
Severe neutro- penia in a patient treated with imipenem/cilastatin. Eur J Clin Microbiol In- fect Dis. 1993;12:303-4.Farias MC, de Vega T, Garmendia J, et al. Severe neutropenia in apatient treated with imipenem/cilastatin [J]. Eur J Clin Microbiol InfectDis, 1993,12(4) :303....
亚胺培南,西司他丁钠 活性成分(英) imipenem, cilastatin 全球最高研发状态 上市 中国最高研发状态 上市 原研公司 merck sharp & dohme corp. 中国首次上市年份 / 首次上市国家 / 首次上市年份 / 治疗疾病 / 靶点 作用机制 bacterial penicillin-binding protein inhibitors (细菌青霉素结合蛋白家族抑制剂);enzymes ...
Cilastatin is an enzymatic dipeptidase-1 (DPEP-1) inhibitor originally developed in the early 80s by Merck Sharp & Dohme Research Laboratories (MSDRL) to limit the renal metabolism of imipenem, a β-lactam antibiotic used for the treatment of systemic infec...
Imipenem/cilastatin was chosen as the comparative agent because it has a wide spectrum of activity, it is effective in the treatment of hospitalized patients with intra-abdominal infections, and is widely available and used in the treatment of cIAI. In the current trial, tigecycline monotherapy ...
亚胺培南西司他丁钠混合粉药品报告提供了亚胺培南西司他丁钠混合粉的各种信息,包括亚胺培南西司他丁钠混合粉的药品简介,新药研发进度,仿制药申报进度,中国药品注册情况,一致性评价进度,药品临床试验进度,药品上市等信息.更多药物报告的查询就在戊戌数据药物报告数据库.
Accordingly, 825 patients (413 tigecycline, 412 imipenem/cilastatin) comprised the mITT (safety) population. The majority of the mITT population (98%; 807 of 825) had clinical evidence of a complicated intra-abdominal infection (clinical mITT population). Within this latter cohort, 692 patients ...
cefepime的功效,一个新广谱头孢菌素一、是与去年相比cefpirome,cefatazidime、抗万古霉素,imipenem-cilastatin和青霉素g的一个老鼠的心内膜炎所造成的一个示范型易受应力消除的金黄葡萄球菌。 翻译结果5复制译文编辑译文朗读译文返回顶部 cefepime效力,新的宽广光谱头孢菌素,在葡萄状球菌-奥里斯2,6 -二甲氧基苯青霉素易受...
百度试题 题目CRE所致肾盂肾炎首选药物为 A.Ceftazidime-avibactamB.Meropenem-vaborbactamC.Imipenem-cilastatin-relebactamD.CefiderocolE.以上均正确相关知识点: 试题来源: 解析 E 反馈 收藏
Imipenem / Cilastatin: Experience with a Long-Acting Intramuscular Formulation - Karger PublishersOncology