It is an antifungal antibiotic active in vitro against most dermatophytes and has been the drug of choice for chronic infections caused by these fungi (e.g., nail infections with Trichophyton rubrum) because it is orally administered and presumably incorporated into actively growing tissue. It is...
Compared with imidazole antifungal, ciclopirox has strong penetration ability in cuticle where skin fungus survive, so it has a significant inhibition effect on the cuticle deep fungi, such as onychomycosis. Mainly it is used in clinical for superficial skin fungal infections, such as ringworm, athle...
PRESCRIBED FOR: Penlac Topical Solution 8% is topical therapy without systemic side effects to treat finger or toenail fungus that does not involve the white portion of the nail (lunula) in persons with normal immune systems. In controlled clinical trials it was found to be safe and effective ...
Onychomycosis, which is progressive or recurrent fungal infection, refers to all injections caused by fungus including dermatophyte and yeast fungus. This disease is characterized in that in general, injections caused by this disease start from the nail bed and progresses to the nail plate. Onychomy...
A possible reason for the weaker effect of tavaborole could also be its higher MIC compared with efinaconazole. The in vivo efficacy of efinaconazole 10% solution, tavaborole 5% solution, and ciclopirox 8% nail lacquer were evaluated in a guinea pig onychomycosis model. The results obtained showed...