Human MSCs may respond to TLR ligation, and recent research has suggested that many tissues contain tissue-specific MSCs, possibly located in periendothelial and perivascular regions. At present, the functional consequences of these findings are unclear. We hypothesized that tissue-specific MSCs could ...
The pancreas is of endodermal origin and is generally divided into into two distinct types of glandular tissue with distinct function- paracrine (secrete enzymes into the intestine) and exocrine (secrete hormones into the bloodstream). The exocrine, enzyme-secreting cells are arranged as clusters ca...
Polarized tissues, such as tubular epithelia, form and are regulated by various mechanisms, which enable the formation of luminal structures. The extracellular matrix is a key determinant of tissue-polarity establishment, orientation and maintenance. Abstract How do animal cells assemble into tissues and...
Although microgravity has negative impacts on the physiological process of the human body, more and more attention has been given to the application of microgravity in biomedicine field. For example, cells cultured under microgravity conditions exhibit the formation of 3D tissue-like structures, which ...
(1) theseminiferous tubules, which contain the spermatogonial cells, and which differentiate into the spermatozoa (sperm), and theSertoli cells, which provide support and nutrition to the developing sperm, produce androgen-binding protein to bind the male sex hormone testosterone (and produce a...
Eccrine sweat glands play an essential role in regulating body temperature. Sweat is produced in the coiled secretory portion of the gland, which is surrounded by obliquely aligned myoepithelial cells; the sweat is then peristaltically transported to the
This invading extraembryonic mesoderm contains a heterogeneous mix of cells thought to contain the progenitors for villous core lineages across gestation [12]. Endothelial cell cords are seen within early villi from ∼15 dpc (Fig. 1) [9,13]. The first fetal capillaries appear around 18–20 ...
Cells of carcinoid tumors which arise in the glandular stomach of old male and female Praomys (Mastomys) natalensis contain argyrophil granules when tissues fixed in formalin are colored with solutions of silver salts. The carcinoids met... KC Snell,HL Stewart - 《Science》 被引量: 145发表: ...
(SCJ) epithelium results in preferential formation of metastatic poorly differentiated neoplasms, which are similar to human gastroesophageal carcinoma. Unlike transformation-resistant antral cells, SCJ cells contain a highly proliferative pool of immature Lgr5−CD44+cells, which are prone to ...
Tissues with a fast turnover, such as epidermis or intestine, contain cells with a lifetime of days or weeks, and while they are more easily exposed to insult because of their proximity to the external environment, their natural morphology allows a fast disposal route of cell debris: a direc...