内分泌信号(Endocrine signaling):信号分子(如激素)由内分泌腺或其他组织分泌到血液中,通过血液循环作用于全身各处的靶细胞。 旁分泌信号(Paracrine signaling):信号分子(如局部介质)由一种细胞分泌到周围的细胞间隙,通过扩散作用于邻近的靶细胞。 自分泌信号(Autocrine signaling):信号分子由一种细胞分泌并作用于自身或...
Signaling through these pathways supports the pluripotent state, which relies predominantly upon three key transcription factors: Oct-4, Sox2, and Nanog. These transcription factors activate gene expression of ESC-specific genes, regulate their own expression, suppress genes involved in differentiat...
Ligand-receptor systems, covalent modification cycles, and transcriptional networks are basic units of signaling systems and their steady-state properties are well understood. However, the behavior of such systems before steady-state is poorly characteri
#> Signaling role analysis on the aggregatedcell-cell communicationnetwork from all signaling pathways #> Signaling role analysis on the aggregated cell-cell communication network from all signaling pathways patchwork::wrap_plots(plots = gg) image.png 从散点图中,我们可以看到与 NL 相比,Inflam.DC 和...
Schematic diagram of the MAPK signaling pathway. Figure generated using FigDraw online platform (www.figdraw.com) with an export ID of RYYROb03b9 Full size image As one of the most ancient signal transduction pathways, MAPK cascades exhibit a central role in innate immune responses, ranging fr...
49. SARS-COV-2 cellular entry diagram 50. SREBP Mediated Lipid Metabolism 51. SUMO Pathway 52. TCA Cycle 53. TGF-beta Signaling Pathway 54. Toll-like Receptor Pathway 55. VEGF Signaling Pathway 56. Wnt Signaling Pathway 好啦,以上就是全部的通路海报内容,每一个都是参考了大量文献绘制而成,希望...
Table 1 Roles of Sertoli cells signaling pathways in spermatogenesis Full size table Fig. 1: Schematic diagram illustrating the integrated influence of the TGF-β/Smad, AMPK, and MAPK signaling pathways in SCs on spermatogenesis. The TGF-β/Smad signaling pathway regulates spermatogenesis via controll...
Expression of a variety of molecules is used to indicate T cell function. Both CD69 and CD25 are upregulated via TCR signaling but with distinctive kinetics, with CD69 detectable within hours of TCR ligation and CD25 increasing later. T cell exhaustion, defined by poor effector function and wh...
d Visualization of spatially resolved cell–cell communications, including a heatmap, Sankey plot, and diagram of the LRI from senders to receivers in space, as well as ligand–receptor–target (LRT) signaling pathways over the reconstructed single-cell ST data. Full size image The second ...
(c) Schematic diagram outlining the workflow for RNA sequencing. (d) Gene set enrichment analysis of significant differential pathways between parental cells (H460 and PC9) and GABA-treated cells. (e) Changes in NF-κB pathway-related gene expression in H460 and PC9 cells following GABA ...