In the last two decades, many efforts have been made to better understand the biology of B-lymphoproliferative disorders through the knowledge of physiology and function of the postulated normal counterpart. The follicular mantle B-cells express a typical CD23+ IgM+ IgD+ phenotype and surround the...
的CD5一B 细胞代表体内的主要 B 细胞 .如 向腹 腔中注射抗 RBC 抗体,CD5一B 细胞减少 ,贫血症状也随之减轻。如注射 LPS 可激活 CD5一B 细胞 ,导致贫血加重。但在无 CD5 B细 胞的XID 小鼠中 ,即使用 I SP 刺激后也不会患贫血 。但实验 也表明 CD5 B 细胞 的单 纯产生和聚集对导致 贫...
CD5 B Cells Definition Are a class of atypical, self-renewing B cells found mainly in the peritoneal and pleural cavities in adults. They have a far less diverse receptor repertoire than conventional B cells, and since they are the first B cells to be produced they are also known as B-1...
肝损伤后再生过程中也有CD5B细胞的异常改变.提示CD5B细胞可能具有广泛的临床意义 关键词:CD5B细胞} 自身免疫病{ 自身抗体 中宙分娄号:R392.11 文献标识码:A 文章编号;1008—8199(2001)03—0241—03 Theprogressofstudy0nhumanCD5Bcells YANGRui—ningreviewing.WUJian—guochecking ...
Ann Rheum Dis 2002;61:854-855 High levels of circulating B1a lymphocytes expressing CD5 have been reported in some patients with non-organ-specific autoimmune diseases, such as systemic lupus erythematosus, primary Sjogren's syndrome, and rheumatoid arthritis, although CD5 + B cells do not seem...
Similar to γ/δ T cells in the T cell compartment, CD5 (Lyl) B cells represent a small subset of peripheral B cells which are thought to be involved in the maintenance of natural immunity. In this paper we discuss the main characteristics of CD5 B cells to compare them to those of ...
1 reagents referenced in In leukaemic CD5+ B cells the expression of BCL-2 gene family is shifted toward protection from apoptosis.
B 细胞活化。CD5 + B细胞百分率的增高与肝损伤有密切的伴随关系。 关键词: CD5 + B细胞; 乙型肝炎; 肝功能指标 中图分类号: R575.1 文献标识码: A 文章编号: 100828199(2001)0220099203 ChangeofperipheralbloodCD5 + BcellsinhepatitisBpatientsand ...
B-cells expressing CD5 are associated with the production of autoantibodies and are present at increased levels in several autoimmune diseases. The aim of this study was to investigate the relationship of these cells to the development of type I diabetes and the presence of organ and non-organ-...
Increasing interest has focused on the unique subpopulation of B cells that expresses the CD5 antigen. In this study, we examined the signals that induce the expression of CD5 on normal splenic B cells. Only 12-O-tetradecanoylphorbol-13-acetate (TPA) induced CD5 expression on highly purified ...