3. Charles ED, Brunetti C, Marukian S, Ritola KD, Talal AH, Marks K, Jacobson IM, Rice CM, Dustin LB. Clonal B cells in patients with hepatitis C virus-associated mixed cryoglobulinemia contain an expanded anergic CD21low B-cell subset. Blood. 2011 May 19;117(20):5425-37. 4. Rubts...
一种用于诊断脓毒症的产品,所述产品包括检测cd11c在b细胞中的表达水平的试剂。 在一些具体的实施方式中,上述检测检测cd11c在b细胞中的表达水平的方法可以是流式细胞术,当然也可以是其他本领域所应有的检测方法。 在一些具体的实施方式中,所述cd11c在b细胞中的表达水平通过cd11c和cd19双阳性细胞占cd19单阳性细胞的百...
并且在b细胞中CD11chighB细胞所占的比例与重症度( EDSS )、脑萎缩密切相关 部分脑萎缩在NMO中的病情已经被明确,为了预防脑萎缩的发展,控制CD11chighB细胞参与的慢性炎症可能是有效的。
CD11c(+)B220(+)Gr-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells. Human plasmacytoid dendritic cells (pDCs) are major producers of IFNalpha, are activated by CpG motifs, and are believed to enter lymph nodes (LNs) via L-s... Nakano,Yana...
124961-61-1 牛磺熊去氧胆酸 Dihydroguaiaretic acid 土木香内酯 42895-57-8 松茋 Coumalic acid 24967-93-9 Monomyristin 23513-14-6 野百合碱 100665-43-8 次黄嘌呤 Gentisin 生长激素释放肽-6 岩大戟内酯B 1-咖啡酰奎宁酸 84650-60-2 松脂素-4-O-葡萄糖苷 66648-43-9 BulleyaconitineA 989-23-1...
A growing body of evidence suggests that when B cells are chronically stimulated, a phenotypically unique subset expands. Data suggest that this atypical population contains B cell receptor (BCR) specificities capable of binding the antigen, or sets of antigens that initiated the expansion of these...
The B-ly6 monoclonal antibody specifically binds to the 150 kDa adhesion glycoprotein CD11c (p150, integrin α chain). CD11c is expressed on dendritic cells, monocytes, macrophages, granulocytes, NK cells and subsets of B and T cells. It associates with CD18 to form the CD11c/CD18 complex ...
给CD11c-DTR小鼠腹腔注射DT(白喉毒素),可以完全清除肠道巨噬细胞和树突状细胞,而巨噬细胞和树突状细胞在肠道重新发育回来存在时间窗口期。DT注射后3天后树突状细胞优先发育回来,两周后巨噬细胞才能在肠道中发育回来。利用这种方法我们可以在体内研究巨噬细胞缺失对DSS(葡聚糖硫酸钠)诱导的急性结肠炎的发生发展产生怎样...
目的:检测C D68和C D11c在肝细胞癌(hepatocellular carcinoma,HCC)和癌旁组织巨噬细胞中的表达情况,探讨并比较其与CD68在HCC中的相关临床病理特征的关系及其意义.方法:采用免疫组织化学方法检测60例HCC患者肝癌组织和癌旁组织CD68和CD11c的表达,分析并比较CD68和CD11c在巨噬细胞中的表达情况以及与HCC临床病理特征的关系...
Reactivity: Human Description CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αXand CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells....