参考文献及视频链接: Rajesh M, Mukhopadhyay P, Batkai S, Hasko G, Liaudet L, Drel VR, Obrosova IG, Pacher P (2007) Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrierdisruption. Am J Physiol Heart Circ Physiol 293:H610–H619 Castillo A, Tolon MR, ...
炎性肠病(inflammatory bowel disease,IBD)是一种慢性肠道炎性疾病,包括克罗恩病(Crohn's disease,CD)、溃疡性结肠炎(Ulcerative Colitis,UC)[40],目前认为辅助性T细胞17(Th17)和调节性T细胞(Treg)的失衡是导致IBD发病的重要机制,该病易反复,长期困扰...
CBD has been used in animal model of RA, demonstrating anti-inflammatory and analgesic effects but the mechanism of action has not been identified17,19. Here, we demonstrate that CBD reduces cell viability preferentially in TNF-activated RASF via TRPA1 and mitochondrial targets. CBD might decrease...
CBD is revealed to bind to many receptorsinvolved in regulating the cellular inflammatory response. Due to this, cannabidiol lowers pro-inflammatory cytokines release, preventing inflammation development. Thus, CBD binds to the TRPV1 receptor (one of several inflammation response regulators) and desensit...
ARDS是全身炎症反应综合征(systemic inflammatory response syndrome,SIRS)失控后在肺部的严重表现。在各种有害刺激因子的作用下,机体通过多种途径,如凝血、免疫和下丘脑-垂体-肾上腺轴等,导致SIRS的发生。炎症反应和免疫调节失控引起多形核白细胞、肺泡巨噬细胞等炎症...
Cannabidiol (CBD) is one of more than 100 cannabinoids in the cannabis plant, known to possess anti-inflammatory, neuroprotective, and anti-anxiety properties. Because CBD is non-psychoactive, it will NOT make you high. What are cannabinoids? Cannabinoids are the key chemical compounds of the he...
We hypothesized that 75mg/kg of oral CBD given for 5days after initiation of disease would reduce EAE severity through suppression of either the early peripheral immune or late neuroimmune response. EAE was induced in C57BL/6 mice at two different magnitudes, and peripheral inflammatory and ...
Peripheral blood mononuclear cells (PBMCs) were collected at baseline and T = 90 min, cultured and stimulated with bacterial lipo-polysaccharide (LPS) to induce an inflammatory response. Cell supernatants were assayed for IL-10 and TNF, markers of inflammation, using enzyme-linked immuno-sorbent ...
With its anti-inflammatory properties and THC-free formulation, this gel provides swift and enduring muscle pain relief. The 1:1 ratio of CBD to THC in the roll-on gel ensures a potent solution for fast-acting and sustained ease for sore muscles. ...
There is need for more studies that promote its ability to treat a broad array of cancer-related symptoms, including pain and nausea due to CBD’s anti-inflammatory and anti-anxiety effects. However, a 2009 study showed that CBD with opioids like morphine was effective in pain for cancer pat...