To compare the extent of cartilage deterioration in knees with prior meniscal resection related to trauma versus knees with resection related to degenerative disease, and to compare cartilage deterioration in knees with meniscal surgery to knees without meniscal surgery, controlling for prior knee trauma...
Osteoarthritis, as a degenerative disease, is a common problem and results in high socioeconomic costs and rates of disability. The most commonly affected joint is the knee and characterized by progressive destruction of articular cartilage, loss of extracellular matrix, and progressive inflammation. Me...
Degeneration of the cartilage after anterior cruciate ligament reconstruction (ACL-R) is known, and further deterioration can be expected in patients with tunnel malplacement or partial meniscal resection. It was hypothesized that there is a significant increase in cartilage degeneration after failed ACL...
Degeneration of the cartilage after anterior cruciate ligament reconstruction (ACL-R) is known, and further deterioration can be expected in patients with tunnel malplacement or partial meniscal resection. It was hypothesized that there is a significant increase in cartilage degeneration after failed ACL...
This deterioration of the cartilage ultimately leads to a painful degenerative condition, referred to as osteoarthritis. As perstudies, this condition affects more than 650 million people worldwide and is the leading cause of joint pain. Also Read:Health Benefits of Glucosamine ...
Since cartilage has a minimal ability to repair itself, even in small lesions, if left untreated deterioration to the joint surface may result that can lead to osteoarthritis. 图4. 关节软骨损伤的严重程度outbridge分期:正常0期,I-IV期。
An alternative approach to investigating the correlation between bone and cartilage turnover and deterioration in the pathogenesis in OA is through analysis of the response to various treatments in both preclinical and clinical studies. In particular reference to the notion that cartilage degradation w...
Osteoarthritis (OA) is a very common joint deterioration disease that touches millions of people around the world every day. With an estimated occurrence of 60 % in men and 70 % in women (). Osteoarthritis is a condition sometimes called “wear and tear” arthritis because the joints are aff...
in vivo studies in both animals and humans have a significantly negative effect on cartilage matrix which causes an acceleration of the deterioration of articular cartilage in osteoarthritic joints. The preponderance of evidence shows that NSAIDs have no beneficial ...
the weak spot gives rise to severe arthritis and an artificial knee is the only hope. However, if the problem is caught early, further deterioration could be prevented by a patch repair. Doctoral candidate Meike Kleuskens developed a "training device" to test how such cartilage implants behave...