(FOX 2) - A potentially deadly fungal infection is on the rise, sparking a warning from the CDC as the infection appears to be resistant to most drugs. The deadly infection Candida auris is prompting a warning from the CDC about the potentially deadly fungus. Section Head of Infec...
Candida auris infection: How prepared is Nigeria for this emerging fungal agent?doi:10.4314/AJCEM.V19I1.8S.A FayemiwoO.B. MakanjuolaAJCEM Life line Publishers
Candida aurishas become a serious threat to public health. The mechanisms of how this fungal pathogen adapts to the mammalian host are poorly understood. Here we report the rapid evolution of an adaptiveC. aurismulticellular aggregative morphology in the murine host during systemic infection.C. auri...
Candida auris has globally emerged as a multidrug-resistant fungus linked to healthcare-associated outbreaks. There is still limited evidence on its virulence, pathogenicity determinants, and complex host-pathogen interactions. This study analyzes the in vivo fungal behaviour, immune response, and host...
We aim to share our management experience through this retrospective case series outlining 15 episodes of C auris candidemia identified in 7 patients over 18 months. The initial source of candidemia was central venous catheter in 5 patients, driveline exit site infection in 1 patie...
Ronald DarwinSchool of Pharmaceutical Sciences, Vels Institute of Science Technology & Advanced Studies, Chennai, IndiaShajed Ali AhmedDepartment of Zoology, Assam Brilliant Academy, Simlaguri, AssamTalha Bin EmranDepartment of Pharmacy, BGC Trust University Bangladesh, Chittagong, Bangladesh...
2.4. Infection Model in Galleria mellonella For the infection model,G. mellonellalarvae were used in a weight range of 250 mg ± 30 mg and after a day of fasting. Before injecting with the differentC. aurisstrains, the larvae were washed with 96% ethanol to minimize the surface pathogens....
compromising infection prevention measures in hospitals. In this report, we present the first (reported) case ofC. aurisisolated from a urine sample from a 48-year-old female living in Jordan. The patient succumbed to illness five days following admission to hospital. The isolate was identified ...
auris [32,33]. Antifungal agents play a main role in inhibiting the mechanism of fungal cell wall synthesis or fungal cell membrane synthesis, as fungal cells are wrapped in carbohydrates, which are essential for the growth and fungi survival, for instance, β (1,3)-D-glucan synthases ...
auris, a species that also belongs to the C. haemulonii clade, were resistant to different antifungal classes used, exhibiting MBECs up to 250 times higher than planktonic MICs for amphotericin B and up to 512 times higher for echinocandins (anidulafungin and caspofungin) and azoles (fluconazole...