Cancer cell breakthrough reported by Hebrew U. Scientists identify molecular basis for DNA breakageJUDY SIEGEL
Cancer cell study breakthroughTanya Thompson
Henlius’ pivotal phase 3 clinical study of anti-PD-1 mAb HANSIZHUANG (serplulimab) plus chemotherapy as first-line treatment for previously untreated locally advanced or metastatic squamous non-small-cell lung cancer (sq...
CAR T cell therapy is an effective cancer treatment, but biological and manufacturing hurdles hamper its broad breakthrough. Although the first step towards automated manufacture of CAR cells has been taken, new technologies are needed to enable the treatment of large patient groups. Ulrich Blache ...
through the stimulatory of the interferon genes signaling pathway. It also exhibited remarkable lymph node homing ability and elicited strong TAA-specific T cell responses in mice.169Another way involves the use of lipopolyplex vector, which consists of a bilayer structure with polymer- and ...
While high-throughput drug screening offers possibilities to profile phenotypic responses of hundreds of compounds, elucidation of the cell context-specific mechanisms of drug action requires additional analyses. To that end, we developed a computational target deconvolution pipeline that identifies the key...
following the publication in 2003 of the first complete full-length sequence of thehuman genome. The breakthrough gave tremendousimpetusto the development ofDNA sequencingtechnologies and to the computational approaches needed to analyze large volumes of data (a single human genome sequence yields three...
Process of CAR T-cell therapy. The therapy involves the modification of the T-cell of the patient. Here, the blood is collected through the vein and sent into the apheresis (Not present in the diagram) where it separates along with the white blood cell. The remanent of the blood is infu...
Therefore, the development of lymphocytes from other sources is considered a breakthrough. Recently, induced pluripotent stem cell (iPSC) technology has expanded the sources and doses of primary lymphocytes. Perhaps due to epigenetic memory, compared to somatic cells, iPSCs from cord blood or ...
The war against cancer traces back to the signature event half-a-century ago when the US National Cancer Act was signed into law. The cancer crusade costs trillions with disappointing returns, teasing the possibility of a new breakthrough. Cure for cance