The Janus kinase/signal transducer and activator of transcription cascade transduction (JAK/STAT) signaling pathway is highly conserved in mammals, but the pattern recognition receptors (PRRs) and their functions are unclear. We found that the expression pattern of Bombyx mori C-type lectin 5 (BmC...
We found that the expression pattern of Bombyx mori C-type lectin 5 (BmCTL 5) had a synergy relevance with the JAK/STAT signaling pathway against Beauveria bassiana. An RNAi assay, subcellular localization analysis, yeast two-hybrid technique, protein recruitment experiment and pathogen infection ...
G q pathway regulates proximal C-type lectin-like receptor-2 (CLEC-2) signaling in platelets G q pathway regulates proximal C-type lectin-like receptor-2 (CLEC-2) signaling in plateletsdoi:10.1074/jbc.m117.791012BLOOD platelets... R Badolia,V Inamdar,BK Manne,... - 《Journal of ...
signaling pathways, and function [10]. Defined by their hallmark C-type lectin binding domain (a double-looped, two stranded antiparallel beta-sheet) aka a CTLD, this family of over 1000 mammalian members have been classified into 17 subfamilies, grouped by structural...
SIGN-R1, a C-type lectin that is highly expressed in a subpopulation of MZMs, regulates the complement fixation pathway by interacting with C1q, to fight blood-borne Streptococcus pneumoniae. Therefore, we examined whether the SIGN-R1-mediated classical complement pathway plays a role in apoptotic...
Aggretin, a C-Type Lectin Protein, Induces Platelet Aggregation via Integrin α2β1 and GPIb in a Phosphatidylinositol 3-Kinase Independent Pathway☆ Author links open overlay panelChing-Hu Chung 1, Hui-Chin Peng, Tur-Fu HuangShow more Add to Mendeley Share Cite...
(2013) A C-type lectin receptor pathway is responsible for the pathogenesis of acute cyclophosphamide-induced cystitis in mice. Microbiology and Immunology , n/a-n/a /Dejima, T., K. Shibata, H. Yamada, A. Takeuchi, H. Hara, M. Eto, et al. 2013. AC-type lectin receptor pathway is ...
QiangLouWeiZhangGuangchaoLiuYuanfangMaEBSCO_AspPlos OneThe C-type lectin OCILRP2 costimulates EL4 Tcell activation via the DAP12-Raf-MAP kinase pathway. Lou Q,Zhang W,Liu G,Ma Y. PLo S One . 2014
C-type lectin receptor (CLRs)AdaptorsSignal relationshipAs one family of pattern recognition receptors (PRRs), The C-type lectin receptors (CLRs) play a key role in the anti-fungal infection. The CLR pathway signaling is relayed by adaptor complex which comprises CARD9, BCL10 and MALT1. ...
C-typelectinEsLecHAntimicrobialpeptideJNKC-type lectins (CTLs) are pattern recognition proteins that play significant roles in the innate immune system by identifying and eliminating pathogens. Here, we have reported a CTL (EsLecH) from the Chinese mitten crab that can bind to microorganisms and ...