The C.DIFF CHEKTM is an enzyme immunoassay for use as a screening test to detect C. difficile antigen, glutamate dehydogenase, in fecal samples. The goals of this evaluation were to determine the sensitivity, specificity, positive predictive value, negative predictive value and correlation of ...
The C.DIFF CHEKTM is an enzyme immunoassay for use as a screening test to detect C. difficile antigen, glutamate dehydogenase,in fecal samples. The goals of this evaluation were to determine the sensitivity, specificity, positive predictivevalue, negative predictive value and correlation of the ...
All C. difficile isolates were typed by PCR ribotyping, and the isolates were classified as toxigenic or non-toxigenic based on the empirical knowledge of the association between toxin-positivity and ribotype. The overall sensitivity, specificity, and positive and negative predictive values were ...
CDI was defined as a physician diagnosis of diarrhea plus a positive C difficile test between day -10 and day +100 of allo-HSCT. During the study period, our institution used several C difficile tests: (a) C. Diff Quik Chek -TechLab, Blacksburg VA; (b) BD GeneOhm Cdiff assay, BD ...
Vimentin staining of tubular cross-section was assessed in 50 consecutive fields ( Â 250) using 0, no positive cells; 1 þ , few (1 or 2) positive tubular cells in the tubule; 2 þ , 42, but less than half of cells stained; 3 þ , more than half of cells stained in the...
DIFF QUIK CHEK COMPLETE® test (Alere North America, Inc.). Samples were considered positive if both GDH and toxin antigens were detected. Those that were inconclusive by this method (GDH antigen positive, toxin negative) were reflexed to a molecular detection method which evaluated the ...
The area under the curve (“AUC”) of a ROC plot is equal to the probability that a classifier will rank a randomly chosen positive instance higher than a randomly chosen negative one. The area under the ROC curve may be thought of as equivalent to the Mann-Whitney U test, which tests...
2012. Role of fecal Clos- tridium difficile load in discrepancies between toxin tests and PCR: is quantitation the next step in C. difficile testing? Eur. J. Clin. Microbiol. Infect. Dis. 31:3295-3299.Leslie JL, Cohen SH, Solnick JV, Polage CR. Role of fecal Clostridium difficile load...
Specific GPI anchored proteins, such as carcinoembryonic antigen and mesothelin, have been described as potential biomarkers for certain cancers; however, the overall levels of GPI anchored proteins present in plasma from cases of human cancers have not been evaluated. We have developed the use of ...
“Last year a study was published that turned this on its head and appeared to prove that Clostridium difficilestrainsproducing Toxin A alone were innocuous, and that only Toxin B was essential for disease. This had significant implications — already we have seen a move within the diagnostics i...