colmascope colo a vector colour specification colocasia gigantea bl cologne germany colognegermanyorcolon cololejeunea ocelloid cololejeunea roselloi colombia joins the un colombian farmers sue colombiabogota colombo international colon dialysis colonel archibald chr colonel general colonel roy mustang colonel...
( V._elem, lo, hi ); } //匙间 27 // 枂极函数 28 ~Vector() { delete [] _elem; } // 内部空间 29 // 叧读讵问接口 30 Rank size() const { return _size; } //觃模 31 bool empty() const { return !_size; } //刞空 32 int disordered() const; //刞断向量是否已排序 33...
The c-MYC oncogene is activated in over 70% of all human cancers. The intrinsic disorder of the c-MYC transcription factor facilitates molecular interactions that regulate numerous biological pathways, but severely limits efforts to target its function f
Here, we describe the X-ray and cryo-EM structures as well as the identification and characterization ofC-deglycosylation enzymes from intestinal and soil bacteria, and the structural basis of the common C-deglycosylation reaction by the unique enzymes. The generality of theC-glycoside-metabolisms i...
Cyclophilin A allows the allosteric regulation of a structural motif in the disordered domain 2 of NS5A and thereby fine-tunes HCV RNA replication. J. Biol. Chem. 2019. [CrossRef] 79. Rosnoblet, C.; Fritzinger, B.; Legrand, D.; Launay, H.e.; Wieruszeski, J...
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The empty vector was used as a negative control. All plasmids were isolated using TIANprep Mini Plasmid Kit (DP103, TIANGEN, Beijing, China) and transfected using Lipofectamine 3000 Reagent (Thermo Fisher Scientific, Waltham, MA, USA) according to the manufacture’s protocol. After 48 or 72 h...
First of all, we have chosen to compare stable transfected Dsup+ cells to untransfected cells, rather than to empty-vector transfected cells. This has been a conscious decision, since it is known that stable transfection of an empty vector into HEK293 cells, as well as in other cell lines...
the coherent broad faces of the precipitate plates; the transformation dislocations define steps that are two atom layers in height normal to the habit plane and have a Burgers vector at least approximately equivalent to an (伪/6) (112) Shockley partial dislocation in the parent fcc structure. ...
Structure of the disordered C terminus of Rab7 GTPase induced by binding to the Rab geranylgeranyl transferase catalytic complex reveals the mechanism of Rab prenylation. Wu YW, Goody RS, Abagyan R, Alexandrov K. J Biol Chem. 2009 2009 19240028 Structure-based approaches to antibiotic drug disco...