The team compared 19 people with early-stage Parkinson's disease while not on medication with 19 healthy people, matched for age and gender. They found that the Parkinson's patients had much lower connectivity in the basal ganglia. The researchers were able to define a cut-off or threshold l...
The disease-specific accumulation of pathological proteins has long been the major focus of research in neurodegenerative diseases (ND), including Alzheimer’s disease (AD) and related dementias (RD), but the recent identification of a multitude of genetic risk factors for ND in immune-associated ...
The discovery not only helps us map the location of tissues that contribute to the more zen-like properties of the human mind, it could help us better understand the progress of symptoms in neurodegenerative conditions like Parkinson's disease, potentially leading to better forms of therapy. ...
Comprehensive studies using resting state fMRI and a graph theory approach have shown that the statistical properties of endogenous fluctuations are modulated in Alzheimer’s disease47, Parkinson’s disease48, autism spectrum disorders49 and multiple sclerosis50. In this study, in the allodynia mouse ...
On the other hand, too much manganese can result in a condition calledmanganismwhich looks and acts like Parkinson’s disease.[xxviii] You get most of the manganese you need every day from eating seafood, seeds, chocolate, tea, leafy greens, spices, soybeans, pineapple, blueberries and acai...
s disease33, predict the optimal targets of deep brain stimulation34,35, explain epileptic seizures, find a patient-specific epileptogenicity of the brain regions to improve epilepsy surgeries at hospitals36,37,38,39, or develop novel treatments for Parkinson’s disease40. Well-studied physical ...
No abstract is available for this article.doi:10.1002/scin.2015.187006007SaeyTina HesmanJohn Wiley & Sons, LtdScience News
(2021). Prevalence and Clinical Correlates of Comorbid Anxiety and Panic Disorders in Patients with Parkinson’s Disease. Journal of Clinical Medicine, 10(11), 2302. https://doi.org/10.3390/jcm10112302 Article PubMed PubMed Central Google Scholar Erez, A.B.-H., Rothschild, E., Katz, N....
For Figure (C–E), the two-sided P-value was derived from the linear regression used in our GWAS.FGenetic correlation (gc) between the GM, WM, and FC-BAG using the LDSC software. Abbreviation: AD Alzheimer’s disease, ASD autism spectrum disorder, PD Parkinson’s disease, ADHD ...
Dysfunctional circuits were topographically arranged from occipital to frontal, ranging from interconnections with sensorimotor cortices in dystonia, the primary motor cortex in Tourette’s syndrome, the supplementary motor area in Parkinson’s disease, to ventromedial prefrontal and anterior cingulate cortices...