Adrenarche and bone modeling and remodeling at the proximal radius: weak androgens make stronger cortical bone in healthy children. Adrenarche, the physiological increase in adrenal androgen secretion, may contribute to better bone status. Proximal radial bone and 24-h urinary steroid h... T Remer...
The bone, once formed, is maintained dynamically through two different processes, modeling and remodeling [27], which are also employed in bone fracture recovery. In bone modeling process, the new bone is formed without prior bone resorption, while in the bone remodeling process, bone formation ...
W. Bone modeling and remodeling: potential therapeutic targets for the treatment of osteoporosis. Ther. Adv. Musculoskelet. Dis. 8, 225–235 (2016). CAS PubMed PubMed Central Google Scholar Seeman, E. Age- and menopause-related bone loss compromise cortical and trabecular microstructure. J. ...
Visualization of (re)modeling occurring over the 15 day experimental period in the left loaded tibia and right control tibia of young and adultSostKO and LC mice. The newly formed (blue), resorbed (red), and quiescent (yellow) bone can be seen on the periosteal and endocortical surfaces....
[9–11]. Autografts are the ‘gold standard’ in reconstructing small bone defects and have strong osteogenic characteristics relevant to bone healing, modeling, and remodeling [12]. Pain and donor site morbidity as well as other risks such as major vessel or visceral injuries during harvesting ...
During the process of tendon healing after surgical repair, three overlapping phases are commonly recognized inflammation (days 1–7), proliferation (days 3–14), and remodeling (day 10 onward). Along with the tendon healing, the peritendinous adhesion is formed by excessive invasion of granulatio...
R. Ruimerman Modeling and Remodeling in Bone Tissue Technische Universiteit Eindhoven Eindhoven (2005) Google Scholar 35 S.R. Toms, G.J. Dakin, J.E. Lemons, A.W. Eberhardt Quasi-linear viscoelastic behavior of the human periodontal ligament J Biomech, 35 (2002), pp. 1411-1415 View PDFVie...
As mentioned earlier, active osteoclasts are also a crucial component of in-vitro bone modeling; however, the exact optimal cell source for osteoclasts has yet to be defined. There are several cell types that can be differentiated into osteoclast-like cells, such as bone marrow and peripheral bl...
They play a critical role in bone modeling, remodeling, and repair25. MSCs have shown therapeutic use in orthopedics and regenerative medicine26,27. However, transplantation of MSCs to repair bone injury is ineffective owing to the inefficient localization of the cells to the injury site; ...
MicroRNAs emerge as critical post-transcriptional regulators in bone metabolism. We have previously reported in vitro that miR-21 promotes osteogenesis, while studies have also revealed miR-21 as a regulator of osteoclastogenesis and a promoter of osteoc