Alzheimer's disease (AD) is the most common form of dementia. Cellular AD models derived from human pluripotent stem cells are promising tools in AD research. We recently developed human embryonic stem cell-derived AD models which overexpress mutant Presenilin1 genes, and which exhibit AD phenotype...
19 September 2016 BMS-708163 and Nilotinib restore synaptic dysfunction in human embryonic stem cell-derived Alzheimer's disease models Hisae Nishioka1,2, Norie Tooi1, Takehisa Isobe1, Norio Nakatsuji1,3 & Kazuhiro Aiba1,† Alzheimer's disease (AD) is the most common form of dem...