negative binomialThis work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License.Background: Multilevel analysis, in several forms, has been extensively utilized over the past few decades. While utilizing for colorectal cancer (CRC) screening may be unclear, ...
The mutational signatures can be found using non-negative matrix factorization (NMF). To extract the mutational signatures we have to assume a distribution for the observed mutational counts and a number of mutational signatures. In most applications, the mutational counts are assumed to be Poisson ...