For the class of basophils, a high percentage of correlation (100%) was presented due to the low number of cells; according to [16], the percentage of basophils in an adult sample is 0.4% compared to the total number of cells in the sample, while for eosinophils it is 2.3%, for mono...
Anti-Fc(episilon)RI auto antibodies and basophil histamine releasability in chronic idiopathic urticaria. 来自 Semantic Scholar 喜欢 0 阅读量: 50 作者:RA Sabroe,DM Francis,RM Barr,AK Black,MW Greaves 摘要: Circulating functional autoantibodies to the high-affinity IgE receptor (Fc(epsilon)RI) or...
Since several auto-antibodies, IgGs which recognize IgE or the high-affinity IgE receptor (Fc蔚RI) and IgEs against other self-antigens, are detected in CSU patients, they are considered to activate both mast cells in the skin and basophils circulating in the blood. In addi...
For instance, aside from producing autoreactive IgE, patients with systemic lupus erythematosus (SLE) harbor circulating basophils with a heightened activation state accompanied by increased expression of CD203c and HLA-DR [17]. These activated basophils exhibit enhanced migration to the spleen and ...
Centre de Re´fe´rence pour les maladies syste´miques autoimmunes rares; Assistance Publique-Hoˆpitaux de Paris (AP-HP); Paris, France, 10Institut National de la Sante´ et de la Recherche Me´dicale Unite´ 974, Paris, F-75013, France, 11International Associated Laboratory IMP...
At least 30% of patients with this condition have histamine-releasing autoantibodies directed to either IgE or FcεR1, the high-affinity receptor for IgE. Evidence for these antibodies comes from in vivo studies of autoreactivity with the autologous serum skin test (ASST) in which autologous ...