Basophil activation test in cancer patient blood evaluating potential hypersensitivity to an anti-tumor IgE therapeutic candidate Keywords: basophils; BAT; IgE; MOv18; ovarian cancer EN basophils BAT IgE MOv18 ovarian cancer 1 5 5 07/29/20 20200801 NES 200801 To the Editor, Monoclonal anti-tumor...
In univariate analysis, there was significant association of spleen size (p-<0.001), baseline WBC count (p<0.001), percentages of blasts in bone marrow and peripheral blood (p<0.001), percentage of basophils in peripheral blood (p=0.007) with BCR ABL1 (IS) at 3 months as seen in table...
They account for less than 1 % of total peripheral blood leukocytes. During several decades and due to the difficulties to clearly identify these cells, basophils were though to display similar functionalities than tissue mast cells. However, recent development of novel analytic tools allowed ...
In this test, blood samples, which may be as small as 20 µL for each allergen, are pipetted into the wells of an ELISA plate precoated with the suspected allergens. The plate is then incubated at 37°C for up to 1 hour and the resultant histamine release estimated. Basophil ...
When human polymorphonuclear basophils, a type of white blood cell with antibodies of the immunoglobulin E (IgE) type on its surface, are exposed to anti-I... E Davenas,F Beauvais,J Amara,... - 《Nature》 被引量: 1098发表: 1988年 ...
Basophils were analyzed in the whole blood by flow cytometry. The statistical significance as determined by two-tailed Student-t-test is indicated, where NS, non-significant. (c) The correlation between fold-changes in IL-33 and basophils following IVIg therapy. detect secreted IL-33 from IVIg...
test d’activation des basophilesBasophilsallergyhelminthiasisTh2Basophils represent a rare cell population belonging to the myeloid cell lineage. They account for less than 1 % of total peripheral blood leukocytes. During several decades and due to the difficulties to clearly identify these cells, ...
the objective of this study was to investigate whether the level of basophil CD63 expression is correlated with allergen sensitization, serum autoreactivity and basophil reactivity in patients with CSU.#Basophil-enriched leucocytes were separated from the blood of 64 patients with chronic urticaria (54...
Likewise, mast cell activation test (MAT) and the IgE cross-linking–induced luciferase expression (EXiLE) test are developed using primary human blood–derived mast cells (hMCs) generated from CD117+ peripheral blood precursors and the RS-ATL8 cell line developed by expressing FcεRI and the ...
Keywords: basophil activation test;diagnosis;flow cytometry;nonspecific lipid transfer proteins;Pru p 3