To determine folates, vitamin B12 and total homocysteine levels among neonates from mothers of low or high socioeconomic status.We carried out a cross-sectional transversal study comprising 143 neonates from two maternity hospitals in the city of Salvador, Northeast of Brazil. Cord blood samples ...
Cord blood samples were obtained at the time of delivery from newborns from low (group 1,=77) or high (group 2,=66) socioeconomic status. The vitamin B12 and folates were analyzed by electrochemiluminescence immunoassay and by a competitive test using a natural folate-binding protein (FBP),...
It's more likely to affect someone who has anotherautoimmune disorder, such as Addison's disease or vitiligo. Do speak with your doctor about any symptoms you're experiencing and request a blood test to determine if you have a vitamin B12 deficiency. SOURCE:https://www.express.co.uk/life-...
A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells. Proc Natl Acad Sci U S A. 1998;95(22):13217-132209789068PubMedGoogle ScholarCrossref 35. Ulrich CM, Neuhouser M, Liu AY, et al. ...
PERNICIOUS ANEMIA AND RELATED ANEMIAS TREATED WITH VITAMIN B12 - ScienceDirect The biosyntheses of the modified tetrapyrroles heme and adenosylcobalamin are outlined. The two compounds are made via a branched biosynthetic pathway that... E Jones,WJ Darby,JR Totter - 《Blood》 被引量: 0发表: 19...
Mixed leukozytes were prepared from 10 m l of blood by dextran sedimentation; m s were prepared by centrifugation of 4.5 m l of blood on a discontinuous gradient of Ficoll-Hypaque. The cystine content of both leukocyte preparations was determined by a specific binding assay. All values are ...
Figure2illustrates the "untrapping" of L-methyl-THF by vitamin B12. This untrapping regenerates active reduced folate as tetrahydrofolate (THF). DNA-T formation is dependent on 5,10-methylene-THF, which passes its CH3 group to deoxyuridine monophosphate, thus forming thymidine monophosphate (TMP...
conventional tests for serum folate and vitamin B12are appropriate, and specialized metabolite tests are needed when conventional test results are equivocal. However, in the setting of hemolysis or vitamin B12deficiency, the serum folate can be normal despite tissue folate deficiency. There are several...
Keywords: 'aged 80 and over'; Newcastle 85+ Study; red blood cell folate; vitamin B12; FUT2; MTHFR; food groups 1. Introduction B vitamins, specifically folate and vitamin B12, are essential for one-carbon transfer reactions which include amino acid interconversions, RNA and DNA synthesis ...
Paradoxical Increase of Plasma Vitamin B12 and Folates with Disease Severity in Anorexia Nervosa. Int. J. Eat. Disord. 2015, 48, 317–322. [Google Scholar] [CrossRef] Ermens, A.A.M.; Vlasveld, L.T.; Lindemans, J. Significance of Elevated Cobalamin (vitamin B12) Levels in Blood. ...