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Stem cells are a type of cell that mature and specialize into all the other types of cells in the body. When a cell, for example a skin cell, gets damaged in the body, or grows old, stem cells divide to create new skin cells to replace the old ones. This flexible capability of ste...
Stem cells are a population of undifferentiated cells with unique abilities to self-renew and recreate functional tissues. They are primarily classified by their differentiation potential, origin and lineage progression. According to their potency, stem cells can be totipotent, pluripotent, multipotent, o...
An article collection in Stem Cell Research & Therapy. This thematic series focuses on taking stem cells from the lab to the clinic. This collection of articles has not been sponsored and articles have undergone the journal’s standard peer-review process. The Guest Editor and Editors declare no...
The clinical applications of stem cells pose a multitude of problems, including safety, efficacy, information and consent, the right to unproven treatments, the "right to try", costs, access, sustainability, scientific scrupulousness, patents and regulatory aspects, to name but a few. This article...
Gene therapy is a novel therapeutic branch of modern medicine. Its emergence is a direct consequence of the revolution heralded by the introduction of recombinant DNA methodology in the 1970s. Gene therapy is still highly experimental, but has the potentialThomas ZwakaStemcells.nih.gov...
Stem cells are a heterogeneous cell population characterized by their ability of self-renewal and differentiation.Stem cell research at the cell population level can not meet the demand for further understanding the biology and its applications.Recently,the single cell-based technologies are rapidly appl...
The mouse excisional wound healing model has been used extensively to study wound healing and cutaneous regeneration. However, as mouse skin is mobile, contraction accounts for a large part of wound closure. In the mouse excisional wound splinting model,
Mesenchymal stem cells (MSC) have generated a great amount of enthusiasm over the past decade as a novel therapeutic paradigm for a variety of diseases. Currently, MSC based clinical trials have been conducted for at least 12 kinds of pathological condit
Stem cells possess the remarkable capacity to differentiate into diverse cell types, making them ideal candidates for regenerating damaged or diseased tissues. The use of stem cells in tissue engineering offers several advantages over traditional therapies. First, stem cells can be obtained from various...