Biomarkers are detectable molecules that can reflect specific physiological states of cells, organs, and organisms and therefore be regarded as indicators for specific diseases. And the discovery of biomarkers plays an essential role in cancer management from the initial diagnosis to the final treatment...
Typically, the membranes of normal human cells such as mesenchymal stem cells (MSC), macrophages, red blood cells, and platelets were extracted followed by processed onto the surface of NPs because escaping the attack of macrophages is critical for the therapeutic effects of nanomaterials [60, 61...
The traditional biological principle for developing bone biomaterials is to directly stimulate the osteogenic differentiation of osteoblastic lineage cells, the direct effector cells for osteogenesis. This strategy has been successful for the development of bone biomaterials. However, recent progress in bone...
The CSC2 glioma stem cells were cultured as described previously20. All media except that used to culture CSC2 were supplemented with 10% fetal bovine serum (HyClone), 1% penicillin/streptomycin (Welgene, Gyeongsan, Republic of Korea), and 10 μg/ml ciprofloxacin (Santa Cruz Biotech, ...
directly interacting with the cell membrane. Potential application of graphene as a scaffold for the attachment and proliferation of stem cells and neuronal cells is captivating in a tissue regeneration scenario. Fabrication of 2D graphene into a 3D structure is made possible with the help of 3D ...
Persistent luminescence nanoparticles (PLNPs) are unique optical materials that emit afterglow luminescence after ceasing excitation. They exhibit unexpected advantages for in vivo optical imaging of tumors, such as autofluorescence-free, high sensitivit
Persistent luminescence nanoparticles (PLNPs) are unique optical materials that emit afterglow luminescence after ceasing excitation. They exhibit unexpected advantages for in vivo optical imaging of tumors, such as autofluorescence-free, high sensitivit
Aptamer AP-9R was developed by Cell-SELEX for targeting cancer stem cells of lung cancer, and the target protein is revealed as annexin A2. It was recognized as an unfavorable marker in renal, pancreatic, liver, urothelial, and lung cancer [120]. In order to discover blood protein ...
Minimal residual disease (MRD) is determined as persistence of leukemic cells at submicroscopic levels in bone marrow (BM) of patients in complete remission. MRD can be present in collections of hematopoietic stem cell from blood (HSC-B). Using PFC, we have defined patterns of antigen ...
molecules Review Application of Nanomaterials to Enhance Polymerase Chain Reaction Zhu Yang 1,2, Bei Shen 3, Lihuan Yue 3,4, Yuqing Miao 1,*, Yihong Hu 3,* and Ruizhuo Ouyang 1,* 1 Institute of Bismuth and Rhenium Science, School Materials and Chemistry, University of Shanghai for ...