Bacterial resistance to antibiotics is a growing health threat, but its evolution outside laboratory settings is poorly understood. Bacteria living in the human gut are now found to evolve persistent resistance
cell adhesionfilamentous bacteriaAntibiotics are known to promote bacterial formation of enhanced biofilms, the mechanism of which is not well understood. Here, using biolayer interferometry, we have shown that bacterial cultures containing antibiotics that target cell walls cause biomass deposition on ...
Antimicrobials known to be useful in cases of traveler's diarrhea include azithromycin, fluoroquinolones, and rifaximin. They shorten the duration of diarrhea by 24-36 hours. Antibiotics should not be used in STEC infection as they may lyse the bacteria leading to release of Shiga toxin and may...
Silver LL. Does the cell wall of bacteria remain a viable source of targets for novel antibiotics? Biochem Pharmacol. 2006; 71(7): 996 - 1005.Silver, L. L. 2006. Does the cell wall of bacteria remain a viable source of targets for novel antibiotics? Biochem. Pharmacol. 71:996-1005....
The present invention is in the field of a method for producing engineered microorganisms, a method for producing cell wall—targeting antibiotics using said engineered microorganisms, and a product obtainable by said methods. The microorganisms are engineered in that various gene sequences are provided...
The present invention is in the field of a method for producing engineered microorganisms, a method for producing cell wall-targeting antibiotics using said engineered microorganisms, and a product obtainable by said methods. The microorganisms are engineered in that various gene sequences are provided...