Methods: In trauma surgery we could observe the Linezolid treatment of 2 patients with a MRSA infection. After treatment with Vancomycin and further evidence of MRSA the application of Linezolid was continued during 3 weeks accompanied by further microbiologic investigations. Results: In a 73 year ...
Vancomycin has a narrow spectrum of activity, restricted to most Gram-positive bacteria, and is the drug of choice for the treatment of (MRSA). The vancomycin MIC for MRSA is 1–2 mg/L for fully vancomycin-susceptible strains. Vancomycin inhibits peptidoglycan synthesis by binding to the D-...
Present study conclusively shows that vancomycin remains the first choice of treatment for MRSA infection. To preserve its value, use of vancomycin should be limited to those cases where there are clearly needed. DOI: http://dx.doi.org/10.3126/joim.v34i1.9117 Journal of Institute of Medicine,...
It has previously shown potential in avian influenza treatment [112] and has scored 1.13 μM at half maximal concentration against SARS-CoV-2. Additionally, chloroquine has been reported to increase the endosomal pH required for viral fusion, thereby blocking viral infection [[113], [114], [...
Infections, antibiotic treatment and mortality in patients admitted to ICUs in countries considered to have high levels of antibiotic resistance compared to those with low levels / H. Hanberger, M. Antonelli, M. Holmbom // BMC Infection Diseases. - 2014. - N. 14. - P. 513....
MRSA is one of representative resistant strains, and research for its prevention and treatment was carried out.3–5 The concept that MRSA infection presents different indications for treatment and diagnoses of colonization is controversial, but the differential diagnosis between bacterial infection and ...
To determine whether there is a level of methicillin-resistant Staphylococcus aureus (MRSA) prevalence at which a switch from non-glycopeptide to glycopeptide antibiotics for routine prophylaxis is indicated in surgical environments with a high risk of MRSA infection.Major electronic databases were searche...
et al. Impact of infection control interventions and antibiotic use on hospital MRSA: a multivariate interrupted time-series analysis. Int. J. Antimicrob. Agents 30, 169–176 (2007). Article CAS PubMed Google Scholar McGowan, J. E. Jr. Minimizing antimicrobial resistance in hospital bacteria:...
Tachypnea at triage, chronic ulcers, history of MRSA colonization or infection and cellulitis within the past year were independently associated with oral antibiotic treatment failure. Emergency physicians should consider these risk factors when deciding on oral versus intravenous antimicrobial therapy for ...
"Current standard-of-care drugs for the treatment of MRSA infections are limited," said Pilch. "Furthermore, resistance to these drugs is on the rise, and their clinical effectiveness is likely to diminish in the future." Pilch said that TXA709 kills MRSA bacteria in a unique manner unlike...