Anti-Ferroptotic Effects of bone Marrow Mesenchymal Stem Cell-Derived Extracellular Vesicles Loaded with Ferrostatin-1 in Cerebral ischemia-reperfusion Injury Associate with the GPX4/COX-2 AxisCerebral ischemia-reperfusion injuryFerroptosisHippocampal neuronsBone marrow mesenchymal stem cells...
Therapeutic agents capable of effectively and safely mitigating ferroptotic cell death hold the potential to be critical points of future clinical investigations.JOR SpineVahabi, Armanztürk, Anl MuratKll, BünyaminBirim, DerviKaftan cal, GizemDac, TanerArmaan, Güliz...
In conclusion, in the present work we have demonstrated that in subjects with severe HF with reduced ejection fraction, treatment with SGLT-2i is associated with reduced inflammation and pro-inflammatory immune cell infiltration and an anti-inflammatory and anti-ferroptotic shift in the lipid spectr...
Vaccination with early ferroptotic cancer cells induces efficient antitumor immunity. J Immunother Cancer. 2020;8:e001369. Article PubMed PubMed Central Google Scholar Tang D, Kepp O, Kroemer G. Ferroptosis becomes immunogenic: implications for anticancer treatments. Oncoimmunology. 2020;10:1862949....
The recent study suggests that ferroptosis plays a critical role in radiation-induced lung fibrosis (RILF) and ferropto- sis inhibitor liproxstatin-1 alleviates RILF by decreasing fer- roptosis and inflammation via Nrf2-mediated upregulation of HO-1 and GPX4 [67]. One o...
Tau-mediated iron export prevents ferroptotic damage after ischemic stroke. Mol Psychia- try. 2017;22(11):1520–30. 13. Rhim T, Lee DY, Lee M. Drug delivery systems for the treatment of ischemic stroke. Pharm Res. 2013;30(10):2429–44. 14. Samaridou E, Walgrave H, Salta E, ...
ANTI-FERROPTOTIC ACTION OF SULFORAPHANE IN SKELETAL MUSCLE OF DIABETIC MICEAna, StaniMilica, MarkeliNevena, SaviKsenija, VelikoviAnelija, GudeljVesna, MartinoviIlijana, GrigorovVesna, OtaeviGenetics & Applications
Here, we further discuss and evaluate the role of indigo based on the results.Shaopeng,SunMolecular Profiling Research Center for Drug Discovery (Molprof) National Institute of AdvancedBin,LvJournal of gastroenterology
Selenium plays an essential role in reducing lipid peroxidation generated during ferroptosis through its incorporation into the catalytic site of glutathione peroxidase 4. Here, we compared the anti-ferroptotic activity of several organic and inorganic selenium compounds: methylselenocysteine, selenocystine, ...
The antiferroptotic role of TRIM7: Molecular mechanism and synergistic effect with temozolomideferroptosisglioblastomaTRIM7doi:10.1002/cai2.77Luyao WangRongyang XuChengying HuangS. QuCancer Innovation