Conclusion ANA are highly prevalent in elderly patients under SARD suspicion, while the incidence of SARD is very low, which explains the low positive predictive value of ANA testing. Interestingly, only one among the ten cases of SARD confirmed was indeed an ANA-related disease (Sjogren syndrome...
but the positive predictive value for rheumatic disease was low.The false-positive rate for any rheumatic disease was 72%in patients 65 years old or younger, and 90%in patients older than 65 years.Even ANAs that were positive at a titer of 1:320 or greater were more likely to be falsely...
The application gives the method to determine the blank value and titer of sodium fluoride by thermometric titration. NaF is used as a titrant in thermometric precipitation titration forming Elapsolith (NaK2AlF6).