Briefly, FASTA sequences of all identified proteins were retrieved from Uniprot ID mapping online tool, and were used as inputs into the Outcyte online tool (version 1.0; http://www.outcyte.com/)
WO1999001576A1 Jul 2, 1998 Jan 14, 1999 University Of Bristol Method of determining the genotype of an organism using an allele specific oligonucleotide probe which hybridises to microsatellite flanking sequencesWO1999001576A1 1998年7月2日 1999年1月14日 Edwards Keith Joseph Method of determining ...
A genome assembly provides an estimate of the nucleotide order of an organism, but does not directly include the placement of different features of the genome. The location of these features, for instance where the different genes are located in the genome, needs to be determined by a process...
The numbered chromosomes are referred to as autosomes and exist in pairs in every cell, each member of the pair being derived from a parent. Chromosome X and Y have pseudoautosomal regions with distinct recombinatory properties. Through the process of X-inactivation, women selectively inactivate one...
Genomics is the study of an organism’s genome and its structure, function, and evolution. Genomic tools can be used to study genetic diversity in a population, the understanding of which provides strategies for the genetic selection of desirable traits. Genome science has developed rapidly in the...
In all cases, it is based on an organism's genotype at polymorphic loci. This polymorphism is thought to be maintained by a form of balancing selection called negative frequency-dependent selection (Wright, 1939; Kimura and Crow, 1964). Under negative frequency-dependent selection, alleles become...
(PK), describing the quantitative behaviour of the warfarin interacting with the organism, and inpharmacodynamics(PD), describing the effects of drug on the body. This variability contributes to more than ten-fold difference in therapeutic dose in adults and can be partly ascribed also to clinical...