Focus on "An increase in calcium influx contributes to post-tetanic potentiation at the rat calyx of Held synapse." J Neurophysiol 96: 2840 -2841, 2006.Felmy F, von Gersdorff H (2006) Late switch for post-tetanic potentiation: once again it's Ca 2ϩ. Focus on "An increase in ...
Follow up studies using conditional ADAR2 knockout mice and human tissue propose that reduced GluA2 Q/R editing and subsequent increase in AMPAR calcium permeability is responsible for motor neuron deficits in the spinal cord, as well as TDP-43 pathology due to calcium-activated, calpain-induced...
reported that AM RF-EMF can inducecancer cellsto differentiate into quiescent cells and suppresscancer cellproliferation by inducing Ca2+influx through Ca v3·2T-type voltage-gated calcium channels (CACNA1H) resulting in increasedintracellular calciumconcentration withinHCC cellsonly (Jimenez et al. ...
Agonist caused mito- chondrial Ca2 þ transients characterized by a fast initial influx resulting in an increase of 131.1±3.2% (n ¼ 33) of resting Ca2 þ levels that was followed by an efflux (at a rate of 130±24 Â 10 À 3/s) during exposure to the agonist (Figures 2f ...
To this aim, aequorin-based measurements of cytosolic Ca2+ transients were performed to evaluate whether unwanted non-physiological contact sites between the ER and PM eventually could be induced by the expression of the SPLICSS/L-P2AER-PM reporter and thus increase Ca2+ entry. Figure 3a, b ...
The IC(50) values of these blockers for the ET-1-induced mitogenesis were similar to those for the 10 nM ET-1-induced increase in [Ca(2+)](i). In contrast, LOE 908 completely suppressed 0.1 nM ET-1-induced mitogenesis, whereas SK&F 96365 did not affect it.Collectively, these ...
Additionally, it has been observed that during viral infections, pro-inflammatory cytokines can stimulate an increase in the levels of ACE2 protein, the receptor for SARS-CoV-2. A larger quantity of this protein may accelerate the entry of the novel coronavirus into the host cells and contribute...
Increasing levels of intracellular calcium have also been shown to increase MV shedding from tumor cells and EX release from oligodendrocytes and platelets [35,36,37]. Calcium ionophore-induced EV release exhibited protective effects against reperfusion injury in HEK293 cells [38,39]. In addition, ...
Over supplementation of diets with amino acids is costly and can increase the nitrogen emissions from animals. Although in vivo animal assays for quantification of amino acid bioavailability are well established, Escherichia coli-based bioassays are viable potential alternatives in terms of accuracy, ...
Both the adenylyl cyclase/PKA pathway and the calcium influx are involved in 5-HT-induced aldosterone secretion. 展开 关键词: Animals Rats Rats, Wistar Zona Glomerulosa Cytosol Calcium Aldosterone Serotonin GTP-Binding Proteins Adenylate Cyclase ...