Allogeneic Stem Cell Transplant - Virtual Medical CentreVirtual Medical Centre
Allogeneicstem cell transplantationis an established treatment modality for a variety of hematologicmalignancies. Unfortunately, it carries a high risk of complications and toxicities related to the intensive preparative regimen which is traditionally used for pre-transplant myeloablation and thegraft versus ...
PFS was very similar for both sibling and unrelated transplants and there was no difference in PFS between patients with respect to remission status prior to transplantation. Nine (38%) patients experienced acute graft‐versus‐host disease (GVHD) and 14 (58%) experienced chronic GVHD, of which...
Allogeneic stem cell transplant (alloSCT) is a current treatment option for patients with refractory/relapsed classic Hodgkin lymphoma (CHL), including those who have failed an autologous transplantation. We performed a retrospective multicenter analysis of 113 patients (median age 28 years; range 14–...
Acute graft versus host disease (aGvHD), a unique complication of hematopoietic stem cell transplantation, was observed in 55% of patients. In 49% of them the clinical course of aGvHD demanded traeatment. We also analysed transplant related mortality. The main cause of early mortality was acute...
Haploidentical hematopoietic stem cell transplantation for hematologic malignancies: a novel conditioning regimen with anti-T lymphocyte immunoglobulin instead of anti-thymocyte globulin for in vivo T cell depletion Article Open access 14 October 2024 Posttransplant blockade of CXCR4 improves leukemia compl...
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a well-established curative approach for a variety of malignant and nonmalignant hematologic disorders. However, several complications can occur that lead to transplant failure including progression or recurrence of primary disease, gra...
Allogeneic Hematopoietic Stem Cell Transplantions in Blastic Plasmacytoid Dendritic Cell Neoplasm in first complete remission: an effective therapy for a r... We sought to clarify the role of high-dose chemotherapy followed by autologous hematopoietic stem cell transplantation (auto-HSCT) and allogeneic...
Reduced-intensity allogeneic stem cell transplantation in relapsed and refractory Hodgkin's disease: low transplant-related mortality and impact of intensi... A total of 40 patients with relapsed/() underwent reduced-intensity conditioning (RIC) allogeneic stem cell transplantation (allo-) from an HLA...
We report the successful outcome of allogeneic stem cell transplant (SCT) in a patient with acute lymphoblastic leukaemia (ALL) and pulmonary zygomycosis diagnosed prior to transplant. The lesion was surgically excised and SCT proceeded with antifungal therapy, granulocyte transfusions and G-CSF suppor...