Perinatology.comoffers a free online allele frequency calculator. This calculator uses the Hardy-Weinberg equation to estimate the frequency of the carrier state (2pq) for an autosomal recessive trait. All you have to do is add the population that has recessive traits either in percentage or in ...
In population genetics, allele frequency is used to reflect the genetic diversity of a population species. It is also referred to as gene frequency. It is a measure of relative frequency of a gene on a genetic locus in a population. The frequency is expressed in terms of percentage. Hardy-...
Power was computed using TDT Power Calculator [15] varying SNP minor allele frequency (MAF) and genetic relative risk (GRR).doi:10.1371/journal.pone.0104212.t004E. K. AllenA. ManichaikulWei-Min ChenS. RichK. DalyM. SalePLOS ONE
Filtering AF was previously defined as the threshold disease-specific “maximum credible AF” at or below which the disease could not plausibly be caused by that variant14. Filtering AFs were computed using the “inverse AF” calculator of a web-based tool (http://cardiodb.org/allelefrequencyap...
The allele frequency calculator checks how often a gene occurs in the population, based on the prevalence of the disease it causes, using the Hardy-Weinberg equation.
(LD) with theCYP2C9*3allele in a White American population. The aim of the present study is to determine the presence and frequency ofCYP2C9pVNTRin a Spanish population, as well as analyzing whether thepVNTR-Sallele is in LD with theCYP2C9*3allele in this population. Subjects and ...