An enzyme isolated from an organism that metabolizes alpha-galactosyl containing saccharides, comprising an alpha-galactosidase (E.C. 3.2.1.22, alpha-D-galactoside galatohydrolase) with optimal activity in the neutral to alkaline pH range, and which hydrolyzes a variety of alpha-galactose containing...
Alkaline alpha-galactosidaseAn isolated enzyme derived from an alpha-galactosyl saccharide metabolizing organism, the enzyme comprising: (a) an alpha-galactosidase (E.C. 3.2.1.22, alpha-D-galactoside, galactohydrolase) activity; (b) a Km for the substrate raffinose of less than about 17 mM; and...
Alkaline alpha-galactosidasePromoterMaize ALKALINE ALPHA GALACTOSIDASE (ZmAGA) is a key enzyme in the raffinose metabolism pathway. We have previously characterized theZmAGA1gene as heat shock induced in germinating maize seeds. Here, we report thatZmAGA1is induced in maize leaves by heat shock, ...
A method of treating Fabry is provided. The method comprises administering to a subject in need thereof a therapeutically effective amount of alkaline alpha galactosidase, thereby treating Fabry disease.Shaaltiel, YosephBen-moshe, TehilaAzulay, Yaniv...
ALKALINE ALPHA- GALACTOSIDASE HAVING BROAD SUBSTRATE SPECIFICITYAn isolated enzyme derived from an alpha-galactosyl saccharide metabolizing organism, the enzyme comprising: (a) an alpha-galactosidase (E.C. 3.2.1.22, alpha-D-galactoside, galactohydrolase) activity; (b) a Km for the substrate raffinose...
1999. A novel alkaline alpha-galactosidase from melon fruit with substrate preference for raffinose. Plant Physiol. 119:979-988.Gao, Z., and Schaffer, A. A. (1999). A novel alkaline alpha-galactosidase from melon fruit with a substrate preference for raffinose. Plant Physiol. 119, 979-988....
A method of treating Fabry is provided. The method comprises administering to a subject in need thereof a therapeutically effective amount of alkaline alpha galactosidase, thereby treating Fabry disease.doi:US20120230974 A1Yoseph ShaaltielTehila Ben-MosheYaniv Azulay...
Molecular cloning and characterisation of a cDNA encoding a putative alkaline alpha-galactosidase from grapevine (Vitis vinifera L.) that is differentially expressed under osmotic stress. Samia Daldoul,Imen Toumi,Goetz M. Reustle. ACTA PHYSIOLOGIAE PLANTARUM . 2012...
ALKALINE ALPHA-GALACTOSIDASE HAVING BROAD SUBSTRATE SPECIFICITYAn isolated enzyme derived from an alpha-galactosyl saccharide metabolizing organism, the enzyme comprising: (a) an alpha-galactosidase (E.C. 3.2.1.22, alpha-D-galactoside, galactohydrolase) activity; (b) a Km for the substrate raffinose ...
There are provided novel plant-derived enzymes for hydrolysis of sugars and particularly an alkaline alpha-galactosidase which hydrolyzes a broad spectrum of galactosyl-saccharides such as melibiose, raffinose and stachyose and guar gum, at neutral to alkaline pH conditions.Schaffer, Arthur...