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A consequence of gut barrier disruption is the absorption of LPS into the portal circulation and subsequent delivery into the systemic circulation, a condition referred to as endotoxemia. The current study shows that ethanol and corticosterone caused a significant elevation of plasma LPS (Fig. 3A)....
Maternal, infant, and delivery factors associated with neonatal thyroid hormone status. Thyroid 2008; 18: 67–76. 19 Hernandez JT, Hoffman L, Weavil S, Cvejin S, Prange AJ Jr. The effect of drug exposure on thyroid hormone levels of newborns. Biochem Med Metab Biol 1992; 48: 255–262....
Overexpression of Mn-SOD by gene delivery is effective against hepatocyte mitochondrial oxidative stress, and maintenance of mitochondrial GSH and is protective against alcohol-induced liver injury. Thus, preventing the accumulation of oxidants in mitochondria may be an important strategy in reducing ...
These peptide antioxidants represent a novel approach with targeted delivery of antioxidants to the inner mitochondrial membrane. The structural motif of these SS-peptides centers on alternating aromatic residues and basic amino acids (aromatic-cationic peptides) that can scavenge hydrogen peroxide and ...
self-administration study, the rats underwent daily 30 min FR1 sessions. Responses on the right lever resulted in the delivery of 0.1 ml of saccharin (0.04%, w/v). Lever presses on the left lever delivered 0.1 ml of water. This procedure lasted 13 days until a stable baseline ...