Title:Akkermansia muciniphila as a novel probiotic for metabolic health 标题:Akkermansia muciniphila 作为一种新型益生菌对代谢健康的作用 PMID:6699990 URL:https://www.ncbi.nlm.nih.gov/pmc/ar Title:Clinical effects of A. muciniphila on weight loss 标题:Akkermansia muciniphila 对减重的临床效果 PM...
肠道中低浓度的Akkermansia muciniphila可能表明黏液层较薄,从而导致肠道屏障功能减弱,此外还会增加细菌毒素的易位,炎症性肠病、哮喘、肥胖症和 II 型糖尿病患者的Akkermansia muciniphila浓度往往较低。 我们知道整个胃肠道 (GI) 的粘膜完整性对于维持人体健康至关重要。这其中,粘液屏障的完整性是胃肠道的第一道防线。
肠道中低浓度的Akkermansia muciniphila可能表明黏液层较薄,从而导致肠道屏障功能减弱,此外还会增加细菌毒素的易位,炎症性肠病、哮喘、肥胖症和 II 型糖尿病患者的Akkermansia muciniphila浓度往往较低。 我们知道整个胃肠道 (GI) 的粘膜完整性对于维持人体健康至关重要。这其中,粘液屏障的完整性是胃肠道的第一道防线。
肠道中低浓度的Akkermansia muciniphila可能表明黏液层较薄,从而导致肠道屏障功能减弱,此外还会增加细菌毒素的易位,炎症性肠病、哮喘、肥胖症和 II 型糖尿病患者的Akkermansia muciniphila浓度往往较低。 我们知道整个胃肠道 (GI) 的粘膜完整性对于维持人体健康至关重要。这其中,粘液屏障的完整性是胃肠道的第一道防线。
嗜粘蛋白-阿克曼氏菌(Akkermansia muciniphila,A.muciniphila),简称为AKK,于 2004 年发现,是一种从人类粪便中分离出来的椭圆形革兰氏阴性细菌。 该细菌以荷兰微生物生态学家Anton DL Akkermans 的名字命名,以表彰他对该领域的贡献。A. muciniphila 是人类肠道共生菌,并可以依靠肠粘液层的黏蛋白生存。
Akkermansia muciniphila is not only a crucial biomarker that indicates the physiology of human beings but also has huge potential to become a probiotic given its physiological benefits in various clinical scenarios. Current barriers in terms of regulations, necessity for large‐scale clinical ...
嗜粘蛋白-阿克曼氏菌(Akkermansia muciniphila,A.muciniphila),简称为AKK,于 2004 年发现,是一种从人类粪便中分离出来的椭圆形革兰氏阴性细菌。 该细菌以荷兰微生物生态学家Anton DL Akkermans 的名字命名,以表彰他对该领域的贡献。A. muciniphila 是人类肠道共生菌,并可以依靠肠粘液层的黏蛋白生存。
The microbe Akkermansia muciniphila was first isolated two decades ago1 and has emerged as an important member of the complex microbial community in the gastrointestinal tract.2 Over the last decad...
showed that metformin could significantly improve the cognitive function of aged mice and alter the gut microbiota.Akkermansia muciniphila(A. muciniphila), a metformin-associated gut probiotic, improved the cognitive function of aged mice by reducing inflammation both systemically and in the hippocampus...
However, despite its role as a probiotic confirmed by numerous studies and its benefits on host health, very few Akkermansia species are described. In a project to search for new Akkermansia muciniphila strains and analyze their genomic diversity, we discovered two strains that may be members of...