Fallone F; Villard P H; Decome L;.PPARα activation potentiates AhR-induced CYP1A1 expression.Toxicology.2005.122-128F Fallone, PH Villard, L Decome, E Seree, M Meo, C Chacon, A Durand, Y Barra, B Lacarelle, PPARalpha activation potentiates AhR-induced CYP1A1 expression. Toxicology ...
There was significant TF enrichment of the hi-dose downregulated genes for RXR, ESR1, LXR, PPARalpha. At the highest dose, there was also pathway enrichment with upregulated genes for extracellular matrix organization, collagen formation, hemostasis and innate immune system. TCDD demonstrates most ...
The seed ofAlpinia katsumadaiHayata has been used to treat digestive system-related diseases in china for thousands of years. It contains a series of components, such as flavones and volatile oils. The total flavone components have previously been demonstrated to be a potential therapeutic agent for...
Therefore, the aim of this study was to determine both the agonistic and antagonistic endocrine activity of 9 environmentally relevant PAHs using three different CALUX bioassays: The AhR-CALUX, The ER alpha-CALUX and PPAR gamma-CALUX. For the PPAR gamma-CALUX anthracene, fluoranthene, pyrene and ...
Villard PH, Caverni S, Baanannou A, Khalil A, Martin PG, Penel C, Pineau T, Seree E, and Barra Y (2007) PPARalpha transcriptionally induces AhR expression in Caco-2, but represses AhR pro-inflammatory effects. Biochem Biophys Res Com- mun 364:896-901....
4A) such as: regulation of the nuclear factor-erythroid 2-related factor 2 (NRF2)-antioxidant pathway (PRDX1, TALDO, CATA, ITPA, NDPKA, HS90B), role of sirtuin1 and PPAR-γ co-activator-1 α (PGC1)-alpha in activation of antioxidant defence system (GSTP1, PRDX1, CATA), chaperone...
Villard PH, Caverni S, Baanannou A, Khalil A, Martin PG, Penel C, Pineau T, Seree E & Barra Y (2007) PPARalpha transcriptionally induces AhR expression in Caco-2, but represses AhR pro-inflammatory effects. Biochem Biophys Res Commun 364, 896-901....
4A) such as: regulation of the nuclear factor-erythroid 2-related factor 2 (NRF2)-antioxidant pathway (PRDX1, TALDO, CATA, ITPA, NDPKA, HS90B), role of sirtuin1 and PPAR-γ co-activator-1 α (PGC1)-alpha in activation of antioxidant defence system (GSTP1, PRDX1, CATA), chaperone...