INTRODUCTION :Aggressive natural killer cell leukemia (ANKL) is a rare hematologic malignancy characterized by the EBV-driven proliferation of mature natural killer cells. It mostly frequently affects younger adults and has a fulminant course with a median overall survival of 2months. Challenges in ...
To improve the diagnostic accuracy of aggressive NK-cell leukemia (ANKL). Retrospective clinical cases were analysed. The ANKL patients often present with fever, hepatosplenomegaly, jaundice, abnormal liver function and pancytopenia. The disease had an aggressive clinical course. Multiorgan failure and ...
Boysen AK, Jensen P, Johansen P, Dybkær K, Nyegaard M: Treatment of Aggressive NK-Cell Leukemia-A Case Report and Review of the Literature. ... A Kindberg,Boysen,Paw,... - 《Case Reports in Hematology》 被引量: 3发表: 2011年 Aggressive Natural Killer-Cell Leukemia: report of fi...
Aggressive natural killer cell leukemia is an acute, neoplastic proliferation of natural killer (NK) cells resulting in a systemic, progressive disease with a poor prognosis. Establishing an effective standard treatment plan with chemotherapeutic drugs for this disease has had limited success and ...
Mature natural killer (NK) cell neoplasms are classified by the World Health Organization into NK/T cell lymphoma, nasal type (NKTCL), aggressive NK-cellleukemia (ANKCL) and chronic lymphoproliferative disorders of NK-cells, thelatter being considered provisionally. NKTCL and ANKCL are rare disease...
Aggressive natural killer cell leukemia/lymphoma (ANKL) is a rare and aggressive malignancy of natural killer (NK) cells. It is now regarded as a distinct subtype of leukemia as a provisional entity: "NK cell lymphoblastic leukemia/lymphoma" in the 2016 revision to the World Health Organization...
Define aggressive periodontitis. aggressive periodontitis synonyms, aggressive periodontitis pronunciation, aggressive periodontitis translation, English dictionary definition of aggressive periodontitis. n dentistry the inflammation of periodontal tissu
There are three possible scenarios: (1) if KITD816V is the founder mutation, avapritinib should target all abnormal cells and promote re-establishment of normal hematopoiesis, similar to imatinib in chronic phase chronic myeloid leukemia [17]. In our four ASM-AHN cases, we did not observe...
Bone Marrow TransplantationNishizawa M, Sugino N, Matsui Y, Kaneko H, Watanabe M, et al.: Sustained CR of refractory aggressive natural killer cell leu- kemia following unrelated cord blood transplantation. Bone Marrow Transplant 45:1760-1762, 2010...
Aggressive NK-cellleukemia(ANKL) is a cancer in whichleukemia cellsconsist ofnatural killer cells, a part of our immune system in normal conditions. The disease is very rare and aggressive: with the currenttreatment options(cytostatic drugs and hematopoietic stem cell transplantation) patients usually...