Introduction Whereas most patients with aggressive hematological malignancies can achieve disease remission after receiving current standard first-line chemotherapies, the prognosis of those with primary refractory disease remains poor. Conventional salvage chemotherapies are usually unsuccessful, but significant ...
The progression-free survival at 1 year was 46% and was significantly better for those with chemosensitive disease, Hodgkin disease (HD), and low-grade non-Hodgkin lymphoma (NHL). Patients with high-grade NHL, mantle cell lymphoma, or chemoresistant disease had a poor outcome. Reduced-...
SAM Pointed Domain Containing ETS Transcription Factor (SPDEF) is a transcription factor of the ETS family specific for prostate epithelial cells. It has been found to be a transactivator of PSA and is generally associated with regulation of AR activity. In accordance, experimental data have shown ...
What type of chemo is used for liver cancer? What is the most common malignant tumor of the liver? What is the medical term for liver cancer? What is stage 3 liver cancer? What is stage 1 liver cancer? What is stage 4 liver cancer? What is stage 5 liver cancer? What is the most...
Chronic lymphocytic leukemia (CLL) remains an incurable disease. Two recurrent cytogenetic aberrations, namely del(17p), affecting TP53, and del(11q), affecting ATM, are associated with resistance against genotoxic chemotherapy (del17p) and poor outcome
Targeting cell cycle and apoptosis to overcome chemotherapy resistance in acute myeloid leukemia Article 18 November 2022 In vivo PDX CRISPR/Cas9 screens reveal mutual therapeutic targets to overcome heterogeneous acquired chemo-resistance Article Open access 04 November 2022 Combination p53 activation...
Our experiences suggest that a good number of patients benefited from Moga, achieving disease control that was often unattainable by conventional chemotherapies. However, as our statement is based largely on retrospective studies and real clinical practice, it requires further validation. Nevertheless, ...
France] d1-5) or 3 courses every 2 weeks of ACVB (Adriamycin [Pharmacia, Guyancourt, France] 75 mg/m2 d1, cyclophosphamide 1,200 mg/m2 d1, vindesine 2 mg/m2 d1, d5, bleomycin 10 mg d1 and d5, prednisone 60 mg/m2 d1-5) followed by the consolidation and maintenance chemotherap...
Benefit of axicabtagene ciloleucel versus chemoimmunotherapy in older patients and/or patients with poor ECOG performance status with relapsed or refractor... MA Lunning,H Wang,Z Hu,... - 《American Journal of Hematology》 被引量: 0发表: 2024年 Immune reconstitution and infectious ...
Chemoimmu- notherapy with a modified hyper-CVAD and rituximab regimen improves outcome in de novo Philadel- phia chromosome-negative precursor B-lineage acute lymphoblastic leukemia. J Clin Oncol 2010;8: 3880–3889. 12 Chang JE, Medlin SC, Kahl BS, et al. Augmented and standard Berlin-...