The performance of intrinsic signal optical imaging in the visual cortex of mice is described in a recent literature (Zhang et al., 2015). After anesthetized with a mixture (i.p.) of ketamine (0.1 mg/g) and xylazine (0.01 mg/g), the mouse was fixed on the stereotaxic instrument. Anest...
Study Objectives Ketamine and propofol are commonly used for procedural sedation in the emergency department setting. Each of these agents works by a different mechanism of action, and each have adverse effects that are occasionally associated with their use. Propofol sometimes causes respiratory ...
Prolonged nitrous oxide exposure can cause bone marrow depression and life-threatening pressure effects by expansion of air-filled spaces within the body. The idiosyncratic reactions to the intravenous agents include anaphylactoid reactions (which are rare) and triggering of acute porphyria. Emmidate is ...
Drugs used for the induction, maintenance and reversal of anaesthesia carry the risk of adverse reactions. Adverse drug reactions (ADRs) include overdose, adverse and secondary effects, idiosyncratic reactions, drug intolerance and allergic reactions. Reports of severe ADRs in anaesthesia appear to be ...
In patients who may be susceptible to intracranial effects of CO2 retention (e.g., those with evidence of increased intracranial pressure or brain tumors), therapy may reduce respiratory drive, and resultant CO2 retention can further increase intracranial pressure; monitor such patients for signs of...
Discontinue IV infusion immediately if patient complains of pain during injection Respiratory fatalities reported with use in children <2 years (use contraindicated); use lowest effective dose in children aged >2 years; avoid other drugs with respiratory depressant effects Contraindications Hypersensitivity...
Comparison of ephedrine and ketamine in prevention of injection pain and hypotension due to propofol induction. Eur J Anaesthesiol. 2005;22(1): 44–8. 105. Maracaja-Neto LF, Mello Silva GA, de Moura RS, Tibirica E, Lessa MA. Opioid receptor blockade pre- vents propofol-induced hypotension ...
1-1.5 mg/kg; repeat doses of 0.5-0.75 mg/kg in 5-10 minutes up to 3 mg/kg total; follow with 1-4 mg/min continuous infusion Other Indications & Uses Acute management of ventricular arrhythmias (cardiac surgery, acute MI) Off-label: Peds with premature ventricular beats during cardiac ...
Adverse drug reactions (ADRs) are undesirable effects of medications used in normal doses [1]. ADRs can occur during treatment in an intensive care unit (ICU) or result in ICU admissions. A meta-analysis of 4139 studies suggests the incidence of ADRs amo
Corneal Pocket Assay: C57/BL mice (6-8 week old female) were anesthetized with ketamine and a corneal pocket was created in both eyes using a von Graefe cataract knife. Hydron pellets containing basic-FGF with or without test antibody at various doses were then implanted into each eye pocket...