The homozygote AA genotype of the [alpha]1-antichymotrypsin gene may confer protection against early-onset Parkinson's disease in women. Parkinsonism & Related Disorders 2004; 10(8): 469-73.Lin JJ, Yueh KC, Chang CY, Chen CH, Lin SZ (2004) The homozygote AA genotype of the alpha1-...
Would an individual with the genotype Aa have a dominant or recessive phenotype? An individual expresses a trait with the alleles gg. Is this genotype homozygous dominant, homozygous recessive, or heterozygous? Assume a phenotype is determined by one gene with a domi...
Lymphoblastoid cells having the AA genotype had significantly higher IL-8 mRNA expression than cells having the AT or TT genotype (P = 0.022). CONCLUSIONS: Critically ill Caucasian patients who had the AA genotype of IL-8 -251A/T had an increased risk of PaO(2)/FiO(2) <200. The AA ...
Recently, it has been described that human fertility is associated with the interleukin 10 (IL10) -2849 AA genotype. Pre-eclampsia is the most common pregnancy-specific complication. In the pathogenesis of pre-eclampsia, IL10 may affect maternal intravascular inflammation as well as endothelial dysf...
Rasouli, M, Kiany, S - 2007 - S30 - www.sciencedirect.comdoi:10.1016/j.clim.2007.03.261Manoochehr Rasouli and Simin KianyClinical Immunology
在二倍体的细胞或个体内,每一对染色体相同座位上有两个等位基因,如果这两个等位基因是相同的,这种细胞或个体对这个基因座位来讲就称为纯合体(homozygote)。如果这两个等位基因是不同的,就称为杂合体(heterozygous)。一个生物或细胞的全部遗传基因组成该细胞或生物的基因型(genotype)。
We have succeeded in constructing a stable full-length cDNA clone of strain H77 (genotype 1a) of (). We devised a cassette vector with fixed 5' and 3' termini and constructed multiple full-length cDNA clones of H77 in a single step by cloning of the entire , which was a...
Multivariate analysis revealed that the BCL2-938AC/CC genotype (hazard ratio 4.5; p=0.003) was an independent prognostic factor compared to other prognostic factors such as age, histological grade or tumor stage. CONCLUSION: The results suggest a role for the BCL2-938C>A polymorphism as a ...
IFNG+874 AA GENOTYPE IS AN IMPORTANT RISK FACTOR FOR THE DEVELOPMENT OF INVASIVE CERVICAL CANCER (CC) IN MEXICAN WOMENThe data shown here demonstrate the involvement of the A allele and of the AA genotype in the risk of developing ... B Gonzalez,H Flores-A,C Alaez,... - 《Hla》 被引...
37, 38, 39 Importantly, this strategy would provide a treatment for all HD patients independent from their genotype. In this study, we showed that the miHTT construct processed from the miR-451 scaffold is able to strongly suppress mutant HTT aggregation and ultimately dramatically reduce the ...